Implementation of oligonucleotide-gated supports for the electrochemical detection of Ochratoxin A
[EN] We report herein the design a hybrid material for the recognition of Ochratoxin A (OTA) by using an aptamer gated-material able to release electroactive species, which can be measured using differential pulse voltammetry. Mesoporous silica nanoparticles loaded with Methylene Blue and capped wit...
| Autores: | , , , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Fecha de publicación: | 2017 |
| País: | España |
| Institución: | Universitat Politècnica de València (UPV) |
| Repositorio: | RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia |
| Idioma: | inglés |
| OAI Identifier: | oai:riunet.upv.es:10251/102309 |
| Acceso en línea: | https://riunet.upv.es/handle/10251/102309 |
| Access Level: | acceso abierto |
| Palabra clave: | Molecular gates Mesoporous materials Ochratoxin A Sensing Differential pulse voltammetry Electron Microscopy Service of the UPV QUIMICA INORGANICA QUIMICA ANALITICA |
| Sumario: | [EN] We report herein the design a hybrid material for the recognition of Ochratoxin A (OTA) by using an aptamer gated-material able to release electroactive species, which can be measured using differential pulse voltammetry. Mesoporous silica nanoparticles loaded with Methylene Blue and capped with an OTA aptamer were prepared and characterised. A highly selective and sensitive response due to the displacement of the capping aptamer in the presence of OTA and subsequent MB release was found in aqueous media. Finally, the possible use of the gated material for the detection of OTA in a real matrix was also explored. |
|---|