Confirming the presence of 3,4-dihydroxyphenylglycol (DHPG) in olive leaves via thermal extraction and mass spectrometry

8 Páginas.-- 4 Figuras

Detalles Bibliográficos
Autores: Bermúdez-Oria, Alejandra, Rubio-Senent, Fátima, Fernández-Prior, África, Lama Muñoz, Antonio, Rodríguez-Gutiérrez, Guillermo, Fernández-Bolaños Guzmán, Juan
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/406556
Acceso en línea:http://hdl.handle.net/10261/406556
Access Level:acceso abierto
Palabra clave:3,4-Dihydroxyphenylglycol (DHPG)
Antioxidants
Bioactive compounds
Byproduct
Phenolic compounds
Phytochemicals
Valorization
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spelling Confirming the presence of 3,4-dihydroxyphenylglycol (DHPG) in olive leaves via thermal extraction and mass spectrometryBermúdez-Oria, AlejandraRubio-Senent, FátimaFernández-Prior, ÁfricaLama Muñoz, AntonioRodríguez-Gutiérrez, GuillermoFernández-Bolaños Guzmán, Juan3,4-Dihydroxyphenylglycol (DHPG)AntioxidantsBioactive compoundsByproductPhenolic compoundsPhytochemicalsValorization8 Páginas.-- 4 FigurasOlive leaves, a significant byproduct of Olea europaea cultivation, are a rich source of phenolic compounds. Among these, 3,4-dihydroxyphenylglycol (DHPG) stands out for its potent antioxidant capacity, reportedly surpassing hydroxytyrosol. Despite its potential, DHPG has been consistently elusive in conventional olive leaf extracts, often going undetected or appearing in negligible amounts in literature, which predominantly relies on organic solvent methods. This study investigates the efficient recovery of DHPG from 21 diverse olive cultivars, comparing a thermal extraction method against traditional ethanolic extraction. Our results unequivocally demonstrate that thermal treatment (120 °C, 30 min in autoclave) vastly superiorly enhances DHPG yields across all cultivars, confirming its crucial role in DHPG release. Mass spectrometry analysis indicates that this process mediates the hydrolysis and conversion of DHPG precursors. This robust and sustainable thermal strategy unlocks the full potential of olive leaf biomass, providing a high-value source of DHPG for nutraceutical, pharmaceutical, and functional food applications, thereby addressing a critical gap in olive leaf valorization.This work was supported by the Spanish Ministry of Science, Innovation and Universities (grant number PID2022-142731OB-C21) and the Spanish National Research Council (CSIC) (grant number 2024ICT268).Peer reviewedElsevierMinisterio de Ciencia, Innovación y Universidades (España)Consejo Superior de Investigaciones Científicas (España)Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202520252025info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionhttp://hdl.handle.net/10261/406556reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/PID2022-142731OB-C21Food chemistryhttps://doi.org/10.1016/j.foodchem.2025.146794Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/4065562026-05-22T06:33:51Z
dc.title.none.fl_str_mv Confirming the presence of 3,4-dihydroxyphenylglycol (DHPG) in olive leaves via thermal extraction and mass spectrometry
title Confirming the presence of 3,4-dihydroxyphenylglycol (DHPG) in olive leaves via thermal extraction and mass spectrometry
spellingShingle Confirming the presence of 3,4-dihydroxyphenylglycol (DHPG) in olive leaves via thermal extraction and mass spectrometry
Bermúdez-Oria, Alejandra
3,4-Dihydroxyphenylglycol (DHPG)
Antioxidants
Bioactive compounds
Byproduct
Phenolic compounds
Phytochemicals
Valorization
title_short Confirming the presence of 3,4-dihydroxyphenylglycol (DHPG) in olive leaves via thermal extraction and mass spectrometry
title_full Confirming the presence of 3,4-dihydroxyphenylglycol (DHPG) in olive leaves via thermal extraction and mass spectrometry
title_fullStr Confirming the presence of 3,4-dihydroxyphenylglycol (DHPG) in olive leaves via thermal extraction and mass spectrometry
title_full_unstemmed Confirming the presence of 3,4-dihydroxyphenylglycol (DHPG) in olive leaves via thermal extraction and mass spectrometry
title_sort Confirming the presence of 3,4-dihydroxyphenylglycol (DHPG) in olive leaves via thermal extraction and mass spectrometry
dc.creator.none.fl_str_mv Bermúdez-Oria, Alejandra
Rubio-Senent, Fátima
Fernández-Prior, África
Lama Muñoz, Antonio
Rodríguez-Gutiérrez, Guillermo
Fernández-Bolaños Guzmán, Juan
author Bermúdez-Oria, Alejandra
author_facet Bermúdez-Oria, Alejandra
Rubio-Senent, Fátima
Fernández-Prior, África
Lama Muñoz, Antonio
Rodríguez-Gutiérrez, Guillermo
Fernández-Bolaños Guzmán, Juan
author_role author
author2 Rubio-Senent, Fátima
Fernández-Prior, África
Lama Muñoz, Antonio
Rodríguez-Gutiérrez, Guillermo
Fernández-Bolaños Guzmán, Juan
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Ministerio de Ciencia, Innovación y Universidades (España)
Consejo Superior de Investigaciones Científicas (España)
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv 3,4-Dihydroxyphenylglycol (DHPG)
Antioxidants
Bioactive compounds
Byproduct
Phenolic compounds
Phytochemicals
Valorization
topic 3,4-Dihydroxyphenylglycol (DHPG)
Antioxidants
Bioactive compounds
Byproduct
Phenolic compounds
Phytochemicals
Valorization
description 8 Páginas.-- 4 Figuras
publishDate 2025
dc.date.none.fl_str_mv 2025
2025
2025
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/406556
url http://hdl.handle.net/10261/406556
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/PID2022-142731OB-C21
Food chemistry
https://doi.org/10.1016/j.foodchem.2025.146794
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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