Ni-catalyzed Divergent Cyclization/Carboxylation of Unactivated Primary and Secondary Alkyl Halides with CO2

<p> &nbsp;</p> <p style="margin: 0.0px 0.0px 0.0px 0.0px; font: 10.5px 'Times New Roman'"> A user-friendly Ni-catalyzed reductive</p> <p style="margin: 0.0px 0.0px 0.0px 0.0px; font: 10.5px 'Times New Roman'"> cyclization/carb...

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Detalles Bibliográficos
Autores: Wang, Xueqiang, Liu, Yu, Martin, Ruben
Tipo de recurso: artículo
Fecha de publicación:2015
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2072/305841
Acceso en línea:http://hdl.handle.net/2072/305841
https://doi.org/10.1021/jacs.5b03340
Access Level:acceso abierto
Descripción
Sumario:<p> &nbsp;</p> <p style="margin: 0.0px 0.0px 0.0px 0.0px; font: 10.5px 'Times New Roman'"> A user-friendly Ni-catalyzed reductive</p> <p style="margin: 0.0px 0.0px 0.0px 0.0px; font: 10.5px 'Times New Roman'"> cyclization/carboxylation of <i>unactivated </i>alkyl halides</p> <p style="margin: 0.0px 0.0px 0.0px 0.0px; font: 10.5px 'Times New Roman'"> with CO<span style="font: 7.0px 'Times New Roman'">2 </span>is described. The protocol operates under mild</p> <p style="margin: 0.0px 0.0px 0.0px 0.0px; font: 10.5px 'Times New Roman'"> conditions with excellent chemoselectivity profile and a</p> <p style="margin: 0.0px 0.0px 0.0px 0.0px; font: 10.5px 'Times New Roman'"> divergent <i>syn/anti-</i>selectivity pattern that can be easily</p> <p style="margin: 0.0px 0.0px 0.0px 0.0px; font: 10.5px 'Times New Roman'"> modulated by the substrate utilized.</p>