Pyridinium N-heteroarylaminides: synthesis of N-heteroaryltetramines based on 1,6-bis(phenoxy)hexane and 1,3-bis(phenoxymethyl)benzene
The synthesis of a set of new N-heteroaryltetramines is reported. A regioselective alkylation on the N-exo nitrogen of pyridinium N-(heteroaryl)aminide with the corresponding tetrabromo compounds, followed by a clean N–N bond reduction of the corresponding tetra-salts, allowed an easy and general me...
| Autores: | , , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 2007 |
| País: | España |
| Institución: | Universidad de Alcalá (UAH) |
| Repositorio: | e_Buah Biblioteca Digital Universidad de Alcalá |
| Idioma: | inglés |
| OAI Identifier: | oai:ebuah.uah.es:10017/2689 |
| Acceso en línea: | http://hdl.handle.net/10017/2689 https://dx.doi.org/10.1016/j.tetlet.2007.06.044 |
| Access Level: | acceso abierto |
| Palabra clave: | Regioselective synthesis Molecular recognition Polyamine analogs Ligands Complexes 2-Aminopyridines Derivatives Receptors Chemistry N-(2'-azinyl)aminides Chemistry, Organic Bioquímica Ciencia Biochemistry Science |
| Sumario: | The synthesis of a set of new N-heteroaryltetramines is reported. A regioselective alkylation on the N-exo nitrogen of pyridinium N-(heteroaryl)aminide with the corresponding tetrabromo compounds, followed by a clean N–N bond reduction of the corresponding tetra-salts, allowed an easy and general method to obtain N,N′,N″,N‴-tetrakis(2-heteroaryl)tetramines. |
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