Impact of rotavirus vaccination on seizure hospitalizations in children: A systematic review.

BACKGROUND: Previous studies found conflicting results about the effect of rotavirus (RV) vaccination on seizure hospitalizations in children younger than 5 years old. OBJECTIVES: To evaluate the evidence of the impact of RV vaccination on the prevention of seizure hospitalizations in children. METH...

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Detalles Bibliográficos
Autores: ARASA, J., LOPEZ, M., DIEZ, J., ORRICO, A.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:España
Institución:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
Repositorio:r-FISABIO. Repositorio Institucional de Producción Científica
OAI Identifier:oai:fisabio.fundanetsuite.com:p14071
Acceso en línea:https://fisabio.portalinvestigacion.com/publicaciones/14071
Access Level:acceso abierto
Palabra clave:Rotavirus
Rotavirus vaccines
children
convusions
seizures
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spelling Impact of rotavirus vaccination on seizure hospitalizations in children: A systematic review.ARASA, J.LOPEZ, M.DIEZ, J.ORRICO, A.RotavirusRotavirus vaccineschildrenconvusionsseizuresBACKGROUND: Previous studies found conflicting results about the effect of rotavirus (RV) vaccination on seizure hospitalizations in children younger than 5 years old. OBJECTIVES: To evaluate the evidence of the impact of RV vaccination on the prevention of seizure hospitalizations in children. METHODS: A systematic review was conducted in the electronic database MEDLINE of all observational studies in children younger than 5 years old published since 2006. Two reviewers performed title/abstract, full-text review, and data extraction. RESULTS: Thirteen studies met eligibility criteria. Nine studies reported a significant reduction in seizure hospitalizations upon RV vaccine introduction, three studies reported an absence of significant impact, and one study reported a significant rise in seizure hospitalization after the introduction of RV vaccines. LIMITATIONS: The great variability between study designs, case definitions and potential biases prevent quantifying the impact of RV vaccination against seizure hospitalizations. CONCLUSIONS: RV vaccination might prevent seizure hospitalizations in children; however, robust, and well-designed studies are needed to better determine the strength of this association.Elsevier BV2022info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://fisabio.portalinvestigacion.com/publicaciones/14071VaccineISSN: 13588745ISSNe: 0264410Xreponame:r-FISABIO. Repositorio Institucional de Producción Científicainstname:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)Inglésinfo:eu-repo/semantics/openAccessoai:fisabio.fundanetsuite.com:p140712026-06-11T12:45:17Z
dc.title.none.fl_str_mv Impact of rotavirus vaccination on seizure hospitalizations in children: A systematic review.
title Impact of rotavirus vaccination on seizure hospitalizations in children: A systematic review.
spellingShingle Impact of rotavirus vaccination on seizure hospitalizations in children: A systematic review.
ARASA, J.
Rotavirus
Rotavirus vaccines
children
convusions
seizures
title_short Impact of rotavirus vaccination on seizure hospitalizations in children: A systematic review.
title_full Impact of rotavirus vaccination on seizure hospitalizations in children: A systematic review.
title_fullStr Impact of rotavirus vaccination on seizure hospitalizations in children: A systematic review.
title_full_unstemmed Impact of rotavirus vaccination on seizure hospitalizations in children: A systematic review.
title_sort Impact of rotavirus vaccination on seizure hospitalizations in children: A systematic review.
dc.creator.none.fl_str_mv ARASA, J.
LOPEZ, M.
DIEZ, J.
ORRICO, A.
author ARASA, J.
author_facet ARASA, J.
LOPEZ, M.
DIEZ, J.
ORRICO, A.
author_role author
author2 LOPEZ, M.
DIEZ, J.
ORRICO, A.
author2_role author
author
author
dc.subject.none.fl_str_mv Rotavirus
Rotavirus vaccines
children
convusions
seizures
topic Rotavirus
Rotavirus vaccines
children
convusions
seizures
description BACKGROUND: Previous studies found conflicting results about the effect of rotavirus (RV) vaccination on seizure hospitalizations in children younger than 5 years old. OBJECTIVES: To evaluate the evidence of the impact of RV vaccination on the prevention of seizure hospitalizations in children. METHODS: A systematic review was conducted in the electronic database MEDLINE of all observational studies in children younger than 5 years old published since 2006. Two reviewers performed title/abstract, full-text review, and data extraction. RESULTS: Thirteen studies met eligibility criteria. Nine studies reported a significant reduction in seizure hospitalizations upon RV vaccine introduction, three studies reported an absence of significant impact, and one study reported a significant rise in seizure hospitalization after the introduction of RV vaccines. LIMITATIONS: The great variability between study designs, case definitions and potential biases prevent quantifying the impact of RV vaccination against seizure hospitalizations. CONCLUSIONS: RV vaccination might prevent seizure hospitalizations in children; however, robust, and well-designed studies are needed to better determine the strength of this association.
publishDate 2022
dc.date.none.fl_str_mv 2022
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://fisabio.portalinvestigacion.com/publicaciones/14071
url https://fisabio.portalinvestigacion.com/publicaciones/14071
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier BV
publisher.none.fl_str_mv Elsevier BV
dc.source.none.fl_str_mv Vaccine
ISSN: 13588745
ISSNe: 0264410X
reponame:r-FISABIO. Repositorio Institucional de Producción Científica
instname:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
instname_str Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
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collection r-FISABIO. Repositorio Institucional de Producción Científica
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repository.mail.fl_str_mv
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