Implications of cytokine genes in allergic asthma

Padrón-Morales, J.; García-Solaesa, V.; Isidoro García, María; Hernández-Hernández, L.; García Sánchez, María Asunción; Hincapié López, Gloria Inés; Lorente-Toledano, F.; Dávila González, Ignacio Jesús; Sanz Lozano, Catalina Sofía

Implications of cytokine genes in allergic asthma

[EN] Asthma is a complex disease involving numerous mediator molecules and effector cells, in combination with a range of environmental determining factors. Cytokines play a key role in the physiopathological mechanisms of asthma; the study of the structure, regulation and variations of the genes th...

Descripción completa

Detalles Bibliográficos
Autores:	Padrón-Morales, J., García-Solaesa, V., Isidoro García, María, Hernández-Hernández, L., García Sánchez, María Asunción, Hincapié López, Gloria Inés, Lorente-Toledano, F., Dávila González, Ignacio Jesús, Sanz Lozano, Catalina Sofía
Tipo de recurso:	artículo
Estado:	Versión publicada
Fecha de publicación:	2014
País:	España
Institución:	Universidad de Salamanca (USAL)
Repositorio:	GREDOS. Repositorio Institucional de la Universidad de Salamanca
OAI Identifier:	oai:gredos.usal.es:10366/158886
Acceso en línea:	http://hdl.handle.net/10366/158886
Access Level:	acceso abierto
Palabra clave:	cytokine Asthma immune response polymorphisms asthma phenotypes Genetics Allergy and Immunology 3207.01 Alergias 2409 Genética alergia e inmunología genética

id	ES_dc89b88196c1faaecbf30dd09ffda819
oai_identifier_str	oai:gredos.usal.es:10366/158886
network_acronym_str	ES
network_name_str	España
repository_id_str
spelling	Implications of cytokine genes in allergic asthmaPadrón-Morales, J.García-Solaesa, V.Isidoro García, MaríaHernández-Hernández, L.García Sánchez, María AsunciónHincapié López, Gloria InésLorente-Toledano, F.Dávila González, Ignacio JesúsSanz Lozano, Catalina SofíacytokineAsthmaimmune responsepolymorphismsasthma phenotypesGeneticsAllergy and Immunology3207.01 Alergias2409 Genéticaalergia e inmunologíagenética[EN] Asthma is a complex disease involving numerous mediator molecules and effector cells, in combination with a range of environmental determining factors. Cytokines play a key role in the physiopathological mechanisms of asthma; the study of the structure, regulation and variations of the genes that encode for these molecules is therefore crucial. Cytokines have extremely diverse roles, and exert effects both as activators and inhibitors of the innate and adaptive immune response. Certain modifications in the expression or structure of these molecules, resulting from the presence of polymorphisms, may give rise to deregulation of the mentioned effects, and therefore to a predisposition to develop concrete asthma phenotypes.Fondo Español de Investigación Sanitaria (FIS); FEDER funds; Spanish Society of Allergology and Clinical Immunology; Clinical research aid from the Fondo Caja de Burgos.Elservier202420242014info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://hdl.handle.net/10366/158886reponame:GREDOS. Repositorio Institucional de la Universidad de Salamancainstname:Universidad de Salamanca (USAL)InglésAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:gredos.usal.es:10366/1588862026-06-07T06:28:51Z
dc.title.none.fl_str_mv	Implications of cytokine genes in allergic asthma
title	Implications of cytokine genes in allergic asthma
spellingShingle	Implications of cytokine genes in allergic asthma Padrón-Morales, J. cytokine Asthma immune response polymorphisms asthma phenotypes Genetics Allergy and Immunology 3207.01 Alergias 2409 Genética alergia e inmunología genética
title_short	Implications of cytokine genes in allergic asthma
title_full	Implications of cytokine genes in allergic asthma
title_fullStr	Implications of cytokine genes in allergic asthma
title_full_unstemmed	Implications of cytokine genes in allergic asthma
title_sort	Implications of cytokine genes in allergic asthma
dc.creator.none.fl_str_mv	Padrón-Morales, J. García-Solaesa, V. Isidoro García, María Hernández-Hernández, L. García Sánchez, María Asunción Hincapié López, Gloria Inés Lorente-Toledano, F. Dávila González, Ignacio Jesús Sanz Lozano, Catalina Sofía
author	Padrón-Morales, J.
author_facet	Padrón-Morales, J. García-Solaesa, V. Isidoro García, María Hernández-Hernández, L. García Sánchez, María Asunción Hincapié López, Gloria Inés Lorente-Toledano, F. Dávila González, Ignacio Jesús Sanz Lozano, Catalina Sofía
author_role	author
author2	García-Solaesa, V. Isidoro García, María Hernández-Hernández, L. García Sánchez, María Asunción Hincapié López, Gloria Inés Lorente-Toledano, F. Dávila González, Ignacio Jesús Sanz Lozano, Catalina Sofía
author2_role	author author author author author author author author
dc.subject.none.fl_str_mv	cytokine Asthma immune response polymorphisms asthma phenotypes Genetics Allergy and Immunology 3207.01 Alergias 2409 Genética alergia e inmunología genética
topic	cytokine Asthma immune response polymorphisms asthma phenotypes Genetics Allergy and Immunology 3207.01 Alergias 2409 Genética alergia e inmunología genética
description	[EN] Asthma is a complex disease involving numerous mediator molecules and effector cells, in combination with a range of environmental determining factors. Cytokines play a key role in the physiopathological mechanisms of asthma; the study of the structure, regulation and variations of the genes that encode for these molecules is therefore crucial. Cytokines have extremely diverse roles, and exert effects both as activators and inhibitors of the innate and adaptive immune response. Certain modifications in the expression or structure of these molecules, resulting from the presence of polymorphisms, may give rise to deregulation of the mentioned effects, and therefore to a predisposition to develop concrete asthma phenotypes.
publishDate	2014
dc.date.none.fl_str_mv	2014 2024 2024
dc.type.none.fl_str_mv	info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion
format	article
status_str	publishedVersion
dc.identifier.none.fl_str_mv	http://hdl.handle.net/10366/158886
url	http://hdl.handle.net/10366/158886
dc.language.none.fl_str_mv	Inglés
language_invalid_str_mv	Inglés
dc.rights.none.fl_str_mv	Attribution-NonCommercial-NoDerivatives 4.0 Internacional http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess
rights_invalid_str_mv	Attribution-NonCommercial-NoDerivatives 4.0 Internacional http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv	openAccess
dc.publisher.none.fl_str_mv	Elservier
publisher.none.fl_str_mv	Elservier
dc.source.none.fl_str_mv	reponame:GREDOS. Repositorio Institucional de la Universidad de Salamanca instname:Universidad de Salamanca (USAL)
instname_str	Universidad de Salamanca (USAL)
reponame_str	GREDOS. Repositorio Institucional de la Universidad de Salamanca
collection	GREDOS. Repositorio Institucional de la Universidad de Salamanca
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_	1869421778034491392
score	15,81155

Implications of cytokine genes in allergic asthma

Similares en LA Referencia