Quantitative and qualitative methods of evaluating response to biologics in severe asthma patients: Results from a real-world study

[EN] Asthma is a complex major noncommunicable disease affecting around 333 million people worldwide, both children and adults.New biological therapies for treating severe asthma have remarkably improved disease management. Notwith-standing, one remaining crucial problem is evaluating the response t...

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Detalles Bibliográficos
Autores: Estravís Sastre, Miguel, Pérez Pazos, Jacqueline, Martín Martín, María Jesús, Ramos González, Jacinto, Gil Melcón, María, Martín García, Cristina, García Sánchez, María Asunción, Sanz Lozano, Catalina Sofía, Dávila González, Ignacio Jesús
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Institución:Universidad de Salamanca (USAL)
Repositorio:GREDOS. Repositorio Institucional de la Universidad de Salamanca
OAI Identifier:oai:gredos.usal.es:10366/158778
Acceso en línea:http://hdl.handle.net/10366/158778
Access Level:acceso abierto
Palabra clave:asthma
biologics
Benralizumab
Dupilumab
Mepolizumab
Genetics
Allergy and Immunology
3207.01 Alergias
2409 Genética
alergia e inmunología
genética
Descripción
Sumario:[EN] Asthma is a complex major noncommunicable disease affecting around 333 million people worldwide, both children and adults.New biological therapies for treating severe asthma have remarkably improved disease management. Notwith-standing, one remaining crucial problem is evaluating the response to these treatments. Therefore, adequate measurement of the response to biologics in a holistic manner that integrates clinical variables of interest and quality of life is needed, particularly in identifying super-responder patients (SR). Menzies-Gow et al went more profound in the concept and proposed a consensus to evaluate remission.