An Iodine Catalysed Hofmann-Löffler Reaction
<p> Iodine reagents have been identified as economically and ecologically benign alternatives to transition metals, although their application as molecular catalysts in challenging C_H oxidation reactions has remained elusive. An attractive iodine oxidation catalysis is now shown to promote th...
| Autores: | , |
|---|---|
| Tipo de recurso: | artículo |
| Fecha de publicación: | 2015 |
| País: | España |
| Institución: | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| Repositorio: | Recercat. Dipósit de la Recerca de Catalunya |
| OAI Identifier: | oai:recercat.cat:2072/305786 |
| Acceso en línea: | http://hdl.handle.net/2072/305786 https://doi.org/10.1002/anie.201501122 |
| Access Level: | acceso abierto |
| Palabra clave: | Amination Catalysis C-H functionalization Iodine Oxidation |
| Sumario: | <p> Iodine reagents have been identified as economically and ecologically benign alternatives to transition metals, although their application as molecular catalysts in challenging C_H oxidation reactions has remained elusive. An attractive iodine oxidation catalysis is now shown to promote the convenient conversion of carbon–hydrogen bonds into carbon–nitrogen bonds with unprecedented complete selectivity.</p> <p> The reaction proceeds by two interlocked catalytic cycles comprising a radical chain reaction, which is initiated by visible light as energy source. This unorthodox synthetic strategy for the direct oxidative amination of alkyl groups has no biosynthetic precedence and provides an efficient and straightforward</p> <p> access to a general class of saturated nitrogenated herocycles.</p> |
|---|