An Improved Catalyst for Iodine(I/III)-Catalysed Intermolecular C-H Amination
<p> 1,2-Diiodobenzene is presented as an efficient catalyst precursor for the intermolecular amination of arenes under homogeneous conditions. <em>N</em>-Troc and <em>N</em>-phthalimido-substituted methoxyamines serve as suitable nitrogen sources providing the correspon...
| Autores: | , , , |
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| Formato: | artículo |
| Fecha de publicación: | 2016 |
| País: | España |
| Recursos: | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| Repositorio: | Recercat. Dipósit de la Recerca de Catalunya |
| OAI Identifier: | oai:recercat.cat:2072/305868 |
| Acesso em linha: | http://hdl.handle.net/2072/305868 https://doi.org/10.1002/adsc.201600191 |
| Access Level: | acceso abierto |
| Palavra-chave: | Amination Arenes C-H Functionalization Catalysis Hypervalent Iodine |
| Resumo: | <p> 1,2-Diiodobenzene is presented as an efficient catalyst precursor for the intermolecular amination of arenes under homogeneous conditions. <em>N</em>-Troc and <em>N</em>-phthalimido-substituted methoxyamines serve as suitable nitrogen sources providing the corresponding aniline derivatives in up to 99% yield and with up to 66:1 regioselectivity. Key for this successful C-N coupling protocol is the strained m-oxo-bridged conformation of the bisiodine(III) catalyst, which induces unparalleled high reactivity.</p> |
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