Olive-derived bioactive combinations: synergistic angiotensin-I-converting enzyme (ACE) inhibition and distinct mechanisms of triterpenic acids and phenolics

13 Páginas.-- 5 Figuras.-- 4 Tablas

Detalhes bibliográficos
Autores: Rubio-Senent, Fátima, Bermúdez-Oria, Alejandra, Fernández-Prior, África, Lama Muñoz, Antonio, Rodríguez-Gutiérrez, Guillermo, Fernández-Bolaños Guzmán, Juan
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2026
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:dnet:digitalcsic_::5aade446a76ed6b1826640e43ebf5cb7
Acesso em linha:http://hdl.handle.net/10261/428071
https://api.elsevier.com/content/abstract/scopus_id/105024259789
Access Level:acceso abierto
Palavra-chave:Angiotens in‐converting enzyme
Anti‐hypertensive
Olive leaf
Olive oil
Phenolic compounds
Triterpenic acids
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spelling Olive-derived bioactive combinations: synergistic angiotensin-I-converting enzyme (ACE) inhibition and distinct mechanisms of triterpenic acids and phenolicsRubio-Senent, FátimaBermúdez-Oria, AlejandraFernández-Prior, ÁfricaLama Muñoz, AntonioRodríguez-Gutiérrez, GuillermoFernández-Bolaños Guzmán, JuanAngiotens in‐converting enzymeAnti‐hypertensiveOlive leafOlive oilPhenolic compoundsTriterpenic acids13 Páginas.-- 5 Figuras.-- 4 TablasCardiovascular diseases, largely driven by hypertension, remain the leading cause of mortality worldwide. Angiotensin-I-converting enzyme (ACE) inhibition is a well-established therapeutic approach; however, synthetic inhibitors are frequently associated with adverse effects. Natural bioactive compounds, particularly those derived from olives, have been proposed as potential alternatives or complementary agents.This work was supported by the Spanish Ministry of Science, Innovation and Universities (grant number PID2022-142731OB-C21) and the Spanish National Research Council (CSIC) (grant number 2024ICT268).Peer reviewedJohn Wiley & SonsSociety of Chemical IndustryMinisterio de Ciencia, Innovación y Universidades (España)Consejo Superior de Investigaciones Científicas (España)Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202620262026info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionhttp://hdl.handle.net/10261/428071https://api.elsevier.com/content/abstract/scopus_id/105024259789reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/PID2022-142731OB-C21Journal of the science of food and agricultureThe underlying dataset has been published as supplementary material of the article in the publisher platform at DOI 10.1002/jsfa.70372https://doi.org/10.1002/jsfa.70372Síinfo:eu-repo/semantics/openAccessoai:dnet:digitalcsic_::5aade446a76ed6b1826640e43ebf5cb72026-05-22T06:33:51Z
dc.title.none.fl_str_mv Olive-derived bioactive combinations: synergistic angiotensin-I-converting enzyme (ACE) inhibition and distinct mechanisms of triterpenic acids and phenolics
title Olive-derived bioactive combinations: synergistic angiotensin-I-converting enzyme (ACE) inhibition and distinct mechanisms of triterpenic acids and phenolics
spellingShingle Olive-derived bioactive combinations: synergistic angiotensin-I-converting enzyme (ACE) inhibition and distinct mechanisms of triterpenic acids and phenolics
Rubio-Senent, Fátima
Angiotens in‐converting enzyme
Anti‐hypertensive
Olive leaf
Olive oil
Phenolic compounds
Triterpenic acids
title_short Olive-derived bioactive combinations: synergistic angiotensin-I-converting enzyme (ACE) inhibition and distinct mechanisms of triterpenic acids and phenolics
title_full Olive-derived bioactive combinations: synergistic angiotensin-I-converting enzyme (ACE) inhibition and distinct mechanisms of triterpenic acids and phenolics
title_fullStr Olive-derived bioactive combinations: synergistic angiotensin-I-converting enzyme (ACE) inhibition and distinct mechanisms of triterpenic acids and phenolics
title_full_unstemmed Olive-derived bioactive combinations: synergistic angiotensin-I-converting enzyme (ACE) inhibition and distinct mechanisms of triterpenic acids and phenolics
title_sort Olive-derived bioactive combinations: synergistic angiotensin-I-converting enzyme (ACE) inhibition and distinct mechanisms of triterpenic acids and phenolics
dc.creator.none.fl_str_mv Rubio-Senent, Fátima
Bermúdez-Oria, Alejandra
Fernández-Prior, África
Lama Muñoz, Antonio
Rodríguez-Gutiérrez, Guillermo
Fernández-Bolaños Guzmán, Juan
author Rubio-Senent, Fátima
author_facet Rubio-Senent, Fátima
Bermúdez-Oria, Alejandra
Fernández-Prior, África
Lama Muñoz, Antonio
Rodríguez-Gutiérrez, Guillermo
Fernández-Bolaños Guzmán, Juan
author_role author
author2 Bermúdez-Oria, Alejandra
Fernández-Prior, África
Lama Muñoz, Antonio
Rodríguez-Gutiérrez, Guillermo
Fernández-Bolaños Guzmán, Juan
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Ministerio de Ciencia, Innovación y Universidades (España)
Consejo Superior de Investigaciones Científicas (España)
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Angiotens in‐converting enzyme
Anti‐hypertensive
Olive leaf
Olive oil
Phenolic compounds
Triterpenic acids
topic Angiotens in‐converting enzyme
Anti‐hypertensive
Olive leaf
Olive oil
Phenolic compounds
Triterpenic acids
description 13 Páginas.-- 5 Figuras.-- 4 Tablas
publishDate 2026
dc.date.none.fl_str_mv 2026
2026
2026
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/428071
https://api.elsevier.com/content/abstract/scopus_id/105024259789
url http://hdl.handle.net/10261/428071
https://api.elsevier.com/content/abstract/scopus_id/105024259789
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/PID2022-142731OB-C21
Journal of the science of food and agriculture
The underlying dataset has been published as supplementary material of the article in the publisher platform at DOI 10.1002/jsfa.70372
https://doi.org/10.1002/jsfa.70372
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv John Wiley & Sons
Society of Chemical Industry
publisher.none.fl_str_mv John Wiley & Sons
Society of Chemical Industry
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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