Generation of a human control iPSC line with a European mitochondrial haplogroup U background

Human iPSC line N44SV.5 was generated from primary normal human dermal fibroblasts belonging to the European mitochondrial haplogroup U. For this purpose, reprogramming factors Oct3/4, Sox2, Klf4, and cMyc were delivered using a non-integrative methodology that involves the use of Sendai virus.

Detalles Bibliográficos
Autores: Galera-Monge, Teresa, Zurita-Díaz, Francisco, González-Páramos, Cristina, Moreno-Izquierdo, Ana, Fraga, Mario F., Fernández, Agustin F., Garesse, Rafael, Gallardo, M. Esther
Tipo de recurso: artículo
Fecha de publicación:2016
País:España
Institución:Universidad Loyola Andalucía
Repositorio:Brújula
OAI Identifier:oai:repositorio.uloyola.es:20.500.12412/7085
Acceso en línea:https://hdl.handle.net/20.500.12412/7085
Access Level:acceso abierto
Palabra clave:Defects of intergenomic communication
Induced pluripotent stem cells
iPSC
iPS cells
POLG
Descripción
Sumario:Human iPSC line N44SV.5 was generated from primary normal human dermal fibroblasts belonging to the European mitochondrial haplogroup U. For this purpose, reprogramming factors Oct3/4, Sox2, Klf4, and cMyc were delivered using a non-integrative methodology that involves the use of Sendai virus.

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