Dataset with controls for twitching motility and CavA effect on natural transformation [Dataset]

A–Twitching motility of ΔcavA related strains showing that miniTn7 EV has no impact on A. baumannii motility. B–Natural transformation of ΔcavA mutant was bellow the detection limit (< d. l.) and was significantly decreased compared to the WT AB5075. ns p>0.05, ** p<0.01, ***p<0.001, ***...

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Detalles Bibliográficos
Autores: Harkova, Lyuboslava G., Dios, Rubén de, Rubio, Alejandro, Pérez-Pulido, Antonio J., McCarthy, Ronan R.
Tipo de recurso: conjunto de datos
Estado:Versión publicada
Fecha de publicación:2024
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/373235
Acceso en línea:http://hdl.handle.net/10261/373235
Access Level:acceso abierto
Palabra clave:Throughput screening approach
Modulating quorum sensing
Current treatment options
Baumannii &# 8217
Ultimately governing virulence
Adaptive antibiotic resistance
Opportunistic nosocomial pathogen
High potential target
Acinetobacter baumannii </
Ac ), cava
Baumannii </
Virulence regulation
Increasing resistance
Cava ac
Vivo </
Various aspects
Using drna
Study uncovers
Signalling cascade
Second messengers
Resort antibiotics
Pathogenic success
Mortality rates
Leading position
Inversely regulated
Intrabacterial signalling
High morbidity
Gmp systems
First time
Exopolysaccharide production
Established paradigm
Directly proportional
Cyclic di
Cyclic amp gy
Crucial mediator
Central regulator
Bacterial physiology
Descripción
Sumario:A–Twitching motility of ΔcavA related strains showing that miniTn7 EV has no impact on A. baumannii motility. B–Natural transformation of ΔcavA mutant was bellow the detection limit (< d. l.) and was significantly decreased compared to the WT AB5075. ns p>0.05, ** p<0.01, ***p<0.001, **** p<0.0001—One-Way ANOVA with Tukey post-hoc test (A) and Unpaired t-test (B).