Thermal, chemical and photocatalytic inactivation of Lactobacillus plantarum bacteriophages

The effect of several biocides, thermal treatments, and photocatalysis on the viability of four Lactobacillus plantarum phages was investigated. Times to achieve 99% inactivation (T99) of phages at 63, 72, and 90°C were evaluated in four  suspension media: deMan Rogosa Sharpe broth, reconstituted sk...

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Bibliographic Details
Authors: Briggiler Marcó, Mariángeles, de Antoni, Graciela Liliana, Reinheimer, Jorge Alberto, Quiberoni, Andrea del Lujan
Format: article
Status:Published version
Publication Date:2009
Country:Argentina
Institution:Consejo Nacional de Investigaciones Científicas y Técnicas
Repository:CONICET Digital (CONICET)
Language:English
OAI Identifier:oai:ri.conicet.gov.ar:11336/101901
Online Access:http://hdl.handle.net/11336/101901
Access Level:Open access
Keyword:Lactobacillus plantarum
BACTERIOPHAGE INACTIVATION
HEAT TREATMENT
BIOCIDES
PHOTOCATALYSIS
https://purl.org/becyt/ford/2.11
https://purl.org/becyt/ford/2
Description
Summary:The effect of several biocides, thermal treatments, and photocatalysis on the viability of four Lactobacillus plantarum phages was investigated. Times to achieve 99% inactivation (T99) of phages at 63, 72, and 90°C were evaluated in four  suspension media: deMan Rogosa Sharpe broth, reconstituted skim milk, a commercial EM-glucose medium, and Tris magnesium  gelatin buffer. The four phages studied were highly resistant to 63°C (T99 > 45 min); however, counts < 10 PFU/ml  were achieved by heating at 90°C for 5 min. Higher thermal resistance at 72°C was observed when reconstituted skim milk  and EM-glucose medium were assayed. Peracetic acid (0.15%, vol/vol) was an effective biocide for the complete inactivation  of all phages studied within 5 min of exposure. Sodium hypochlorite (800 ppm) inactivated the phages completely within 30 min. Ethanol (100%) did not destroy phage particles even after 45 min. Isopropanol did not have any effect on phage viability. Phage counts < 50 PFU/ml were obtained within 180 min of photocatalytic treatment. The results obtained in this work are  important for establishing adequate methods for inactivating phages in industrial plants and laboratory environments.