An Integrated ISFET pH Microsensor on a CMOS Standard Process

We present the design and integration of a nine-pH microsensor array on a single silicon substrate with its own signal readout circuit, integrated in a 0.6-μm commercial standard complementary metal oxide semiconductor (CMOS) process. An ion sensitive field effect transistor (ISFET) has been used as...

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Detalles Bibliográficos
Autores: JOHAN JAIR ESTRADA LOPEZ, ROSA MARIA WOO GARCIA, AGUSTIN LEOBARDO HERRERA MAY
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2013
País:México
Institución:Universidad Autónoma de Yucatán
Repositorio:Repositorio Digital Institucional de la Universidad Autónoma de Yucatán
Idioma:inglés
OAI Identifier:oai:redi.uady.mx:123456789/534
Acceso en línea:http://redi.uady.mx:8080/handle/123456789/534
Access Level:acceso abierto
Palabra clave:info:eu-repo/classification/cti/1
info:eu-repo/classification/cti/7
CMOS
Instrumentation Amplifier
ISFET
PH
Descripción
Sumario:We present the design and integration of a nine-pH microsensor array on a single silicon substrate with its own signal readout circuit, integrated in a 0.6-μm commercial standard complementary metal oxide semiconductor (CMOS) process. An ion sensitive field effect transistor (ISFET) has been used as pH microsensor and an instrumentation amplifier as the read-out circuit. The ISFET structure is conformed by the channel length and ratio of MOS transistor, gate extended and the selective membrane, for which silicon nitride (Si3N4) is employed as an ion selective element. The complete design includes shielding around the pH microsensor and the readout circuit to avoid leakage of current to the substrate. The readout circuit is composed by three operational amplifiers and resistances that form the instrumentation amplifier, with a ±2.5 V bias has a 50 dB gain, power supply rejection ratio (PSSR) of 120 dB and common mode rejection ratio (CMRR) of 127 dB. The complete system is integrated in a 1.12 mm2 silicon area; it presents a 59 mV/pH linearity, within a concentration range of 2 to 12 of pH level, making it a good alternative for biological or medical applications.