GRAPHENE OXIDE-BASED BIOSENSING SYSTEMS FOR THE ANALYSIS OF PATHOGEN-RELATED ANALYTES
"In this dissertation, a biosensing system targeting pathogen-related analytes was developed. The biosensing system comprises 96 microwell plates coated with graphene oxide, which performs as quencher of fluorescence from a specific immunoprobe. The fluorescence of the immunoprobes that do not...
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| Tipo de recurso: | tesis doctoral |
| Estado: | Versión aceptada para publicación |
| Fecha de publicación: | 2023 |
| País: | México |
| Institución: | Centro de Investigaciones en Óptica |
| Repositorio: | Repositorio Institucional CIO |
| Idioma: | inglés |
| OAI Identifier: | oai:cio.repositorioinstitucional.mx:1002/1287 |
| Acceso en línea: | http://cio.repositorioinstitucional.mx/jspui/handle/1002/1287 |
| Access Level: | acceso abierto |
| Palabra clave: | info:eu-repo/classification/Autor/Biosensing info:eu-repo/classification/Autor/Immunoassay info:eu-repo/classification/Autor/Biophotonics info:eu-repo/classification/Autor/Infectious diseases info:eu-repo/classification/Autor/Fluorescence resonance energy transfer info:eu-repo/classification/Autor/Diagnostics info:eu-repo/classification/cti/7 info:eu-repo/classification/cti/33 info:eu-repo/classification/cti/3399 info:eu-repo/classification/cti/339999 |
| Sumario: | "In this dissertation, a biosensing system targeting pathogen-related analytes was developed. The biosensing system comprises 96 microwell plates coated with graphene oxide, which performs as quencher of fluorescence from a specific immunoprobe. The fluorescence of the immunoprobes that do not experiment immunoreactions (antibody-antigen) are deactivated by graphene oxide via non-radiative energy transfer, whereas those immunoprobes undergoing immunoreactions preserve its photoluminescence due to the distance and the low affinity between the immunocomplex and the graphene oxide-coated surface. Additionally, based on the same biosensing strategy, it was developed a paper-based disposable test for bacterial vaginosis detection." |
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