GRAPHENE OXIDE-BASED BIOSENSING SYSTEMS FOR THE ANALYSIS OF PATHOGEN-RELATED ANALYTES

"In this dissertation, a biosensing system targeting pathogen-related analytes was developed. The biosensing system comprises 96 microwell plates coated with graphene oxide, which performs as quencher of fluorescence from a specific immunoprobe. The fluorescence of the immunoprobes that do not...

Descripción completa

Detalles Bibliográficos
Autor: Mariana Denisse Avila Huerta
Tipo de recurso: tesis doctoral
Estado:Versión aceptada para publicación
Fecha de publicación:2023
País:México
Institución:Centro de Investigaciones en Óptica
Repositorio:Repositorio Institucional CIO
Idioma:inglés
OAI Identifier:oai:cio.repositorioinstitucional.mx:1002/1287
Acceso en línea:http://cio.repositorioinstitucional.mx/jspui/handle/1002/1287
Access Level:acceso abierto
Palabra clave:info:eu-repo/classification/Autor/Biosensing
info:eu-repo/classification/Autor/Immunoassay
info:eu-repo/classification/Autor/Biophotonics
info:eu-repo/classification/Autor/Infectious diseases
info:eu-repo/classification/Autor/Fluorescence resonance energy transfer
info:eu-repo/classification/Autor/Diagnostics
info:eu-repo/classification/cti/7
info:eu-repo/classification/cti/33
info:eu-repo/classification/cti/3399
info:eu-repo/classification/cti/339999
Descripción
Sumario:"In this dissertation, a biosensing system targeting pathogen-related analytes was developed. The biosensing system comprises 96 microwell plates coated with graphene oxide, which performs as quencher of fluorescence from a specific immunoprobe. The fluorescence of the immunoprobes that do not experiment immunoreactions (antibody-antigen) are deactivated by graphene oxide via non-radiative energy transfer, whereas those immunoprobes undergoing immunoreactions preserve its photoluminescence due to the distance and the low affinity between the immunocomplex and the graphene oxide-coated surface. Additionally, based on the same biosensing strategy, it was developed a paper-based disposable test for bacterial vaginosis detection."

Similares en LA Referencia