The unexpected sight: improvement of visual function following intracortical microstimulation of the human occipital cortex
We describe the case of a participant in a clinical trial investigating intracortical microstimulation of the visual cortex to provide a limited yet functional sense of vision to the profoundly blind. Prior to his formal enrolment, he was completely blind due to bilateral Non-arteritic Anterior Isch...
| Autores: | , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2026 |
| País: | España |
| Institución: | Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO) |
| Repositorio: | r-FISABIO. Repositorio Institucional de Producción Científica |
| OAI Identifier: | oai:dnet:r-fisabio___::3234b91a3439677c19382c5ef9bd8da0 |
| Acceso en línea: | https://fisabio.portalinvestigacion.com/publicaciones/20654 |
| Access Level: | acceso abierto |
| Palabra clave: | electrical stimulation visual cortex artificial vision |
| Sumario: | We describe the case of a participant in a clinical trial investigating intracortical microstimulation of the visual cortex to provide a limited yet functional sense of vision to the profoundly blind. Prior to his formal enrolment, he was completely blind due to bilateral Non-arteritic Anterior Ischemic Optic Neuropathy. Following the initiation of brain electrical microstimulation experiments, he experienced a remarkable recovery of spontaneous vision. The regained sight, after more than 3 years of complete blindness, enabled him to perceive light and motion again and even read large characters and words, enhancing his confidence in mobility and daily activities. We conducted several behavioural and electrophysiological tests to assess and quantify his vision over time. Alfaro et al. report the case of a blind individual who participated in a clinical trial involving intracortical microstimulation of the visual cortex. Following electrical stimulation, the participant experienced a significant recovery of vision, enabling light perception, motion detection and reading of large characters, thus improving mobility and daily activities. 10.1093/brain/fcaf504_video1 Video Abstract fcaf504media1 6388674390112 |
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