Effects of fasting and refeeding on somatostatin concentration and binding to cytosol from rabbit gastric mucosa

Somatostatin like immunoreactivity and the density of somatostatin binding sites were measured in stomach (fundus and antrum) from either fed, 12 to 96 hours fasted, or 96 hours fasted plus 48 hours refed rabbits. The somatostatin concentration increased in fundic and antral mucosa after 24 h and re...

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Detalhes bibliográficos
Autores: Roca, B., Fernández-Valencia Rodríguez, Rafael|||0000-0003-2599-9204, Arilla Ferreiro, Eduardo
Formato: artículo
Fecha de publicación:1988
País:España
Recursos:Universidad de Alcalá (UAH)
Repositorio:e_Buah Biblioteca Digital Universidad de Alcalá
Idioma:inglés
OAI Identifier:oai:ebuah.uah.es:10017/2363
Acesso em linha:http://hdl.handle.net/10017/2363
https://dx.doi.org/10.1136/gut.29.5.642
Access Level:acceso abierto
Palavra-chave:Somatostatin
Rabbit
Stomach
Mucosa
Bioquímica
Ciencia
Biochemistry
Science
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repository_id_str
spelling Effects of fasting and refeeding on somatostatin concentration and binding to cytosol from rabbit gastric mucosaRoca, B.Fernández-Valencia Rodríguez, Rafael|||0000-0003-2599-9204Arilla Ferreiro, EduardoSomatostatinRabbitStomachMucosaBioquímicaCienciaBiochemistryScienceSomatostatin like immunoreactivity and the density of somatostatin binding sites were measured in stomach (fundus and antrum) from either fed, 12 to 96 hours fasted, or 96 hours fasted plus 48 hours refed rabbits. The somatostatin concentration increased in fundic and antral mucosa after 24 h and reached its highest value after 96 h of fasting. The number of specific somatostatin binding sites with high and low affinity decreased with the duration of fasting. Refeeding of fasted animals resulted in a normalisation to control values of gastric mucosal somatostatin and somatostatin binding.Instituto de Salud Carlos IIINature Publishing Group19881988-01-01journal articlehttp://purl.org/coar/resource_type/c_6501NAhttp://purl.org/coar/version/c_be7fb7dd8ff6fe43info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10017/2363https://dx.doi.org/10.1136/gut.29.5.642reponame:e_Buah Biblioteca Digital Universidad de Alcaláinstname:Universidad de Alcalá (UAH)InglésengNot available Not available Not availableopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:ebuah.uah.es:10017/23632026-06-18T11:13:07Z
dc.title.none.fl_str_mv Effects of fasting and refeeding on somatostatin concentration and binding to cytosol from rabbit gastric mucosa
title Effects of fasting and refeeding on somatostatin concentration and binding to cytosol from rabbit gastric mucosa
spellingShingle Effects of fasting and refeeding on somatostatin concentration and binding to cytosol from rabbit gastric mucosa
Roca, B.
Somatostatin
Rabbit
Stomach
Mucosa
Bioquímica
Ciencia
Biochemistry
Science
title_short Effects of fasting and refeeding on somatostatin concentration and binding to cytosol from rabbit gastric mucosa
title_full Effects of fasting and refeeding on somatostatin concentration and binding to cytosol from rabbit gastric mucosa
title_fullStr Effects of fasting and refeeding on somatostatin concentration and binding to cytosol from rabbit gastric mucosa
title_full_unstemmed Effects of fasting and refeeding on somatostatin concentration and binding to cytosol from rabbit gastric mucosa
title_sort Effects of fasting and refeeding on somatostatin concentration and binding to cytosol from rabbit gastric mucosa
dc.creator.none.fl_str_mv Roca, B.
Fernández-Valencia Rodríguez, Rafael|||0000-0003-2599-9204
Arilla Ferreiro, Eduardo
author Roca, B.
author_facet Roca, B.
Fernández-Valencia Rodríguez, Rafael|||0000-0003-2599-9204
Arilla Ferreiro, Eduardo
author_role author
author2 Fernández-Valencia Rodríguez, Rafael|||0000-0003-2599-9204
Arilla Ferreiro, Eduardo
author2_role author
author
dc.subject.none.fl_str_mv Somatostatin
Rabbit
Stomach
Mucosa
Bioquímica
Ciencia
Biochemistry
Science
topic Somatostatin
Rabbit
Stomach
Mucosa
Bioquímica
Ciencia
Biochemistry
Science
description Somatostatin like immunoreactivity and the density of somatostatin binding sites were measured in stomach (fundus and antrum) from either fed, 12 to 96 hours fasted, or 96 hours fasted plus 48 hours refed rabbits. The somatostatin concentration increased in fundic and antral mucosa after 24 h and reached its highest value after 96 h of fasting. The number of specific somatostatin binding sites with high and low affinity decreased with the duration of fasting. Refeeding of fasted animals resulted in a normalisation to control values of gastric mucosal somatostatin and somatostatin binding.
publishDate 1988
dc.date.none.fl_str_mv 1988
1988-01-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
NA
http://purl.org/coar/version/c_be7fb7dd8ff6fe43
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10017/2363
https://dx.doi.org/10.1136/gut.29.5.642
url http://hdl.handle.net/10017/2363
https://dx.doi.org/10.1136/gut.29.5.642
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.relation.none.fl_str_mv Not available Not available Not available
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Nature Publishing Group
publisher.none.fl_str_mv Nature Publishing Group
dc.source.none.fl_str_mv reponame:e_Buah Biblioteca Digital Universidad de Alcalá
instname:Universidad de Alcalá (UAH)
instname_str Universidad de Alcalá (UAH)
reponame_str e_Buah Biblioteca Digital Universidad de Alcalá
collection e_Buah Biblioteca Digital Universidad de Alcalá
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,301603

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