Differences in the peripheral blood immune landscape between early-onset and late-onset colorectal cancer

This study aims to discover novel immune biomarkers specific to EOCRC that may permit the development of a non-invasive, peripheral blood-based “liquid Immunoscore” that may integrate specific quantitative measurements. By contrasting the immune landscapes of EOCRC and LOCRC based on key immune cell...

Descripción completa

Detalles Bibliográficos
Autores: Sánchez-Menéndez, Clara, Rodríguez-Pérez, Jaime, Fuertes, Daniel, Leguizamon, Valentina, González-Sanmartin, María, Mateos, Elena, Cervero, Miguel, San José Martínez, Esther, Sanz, Gonzalo, Álvaro, Edurne, Et. al.
Tipo de recurso: artículo
Fecha de publicación:2025
País:España
Institución:Universidad Europea (UEM)
Repositorio:ABACUS. Repositorio de Producción Científica
Idioma:inglés
OAI Identifier:oai:abacus.universidadeuropea.com:11268/16617
Acceso en línea:https://hdl.handle.net/11268/16617
Access Level:acceso abierto
Palabra clave:Neoplasias colorrectales
Diagnóstico precoz
Inmunidad
Cáncer
Medicina preventiva
Investigación médica
Goal 3: Ensure healthy lives and promote well-being for all at all ages
id ES_ee087408dcfee48ce0b2c9c91fc3eb19
oai_identifier_str oai:abacus.universidadeuropea.com:11268/16617
network_acronym_str ES
network_name_str España
repository_id_str
spelling Differences in the peripheral blood immune landscape between early-onset and late-onset colorectal cancerSánchez-Menéndez, ClaraRodríguez-Pérez, JaimeFuertes, DanielLeguizamon, ValentinaGonzález-Sanmartin, MaríaMateos, ElenaCervero, MiguelSan José Martínez, EstherSanz, GonzaloÁlvaro, EdurneEt. al.Neoplasias colorrectalesDiagnóstico precozInmunidadCáncerMedicina preventivaInvestigación médicaGoal 3: Ensure healthy lives and promote well-being for all at all agesThis study aims to discover novel immune biomarkers specific to EOCRC that may permit the development of a non-invasive, peripheral blood-based “liquid Immunoscore” that may integrate specific quantitative measurements. By contrasting the immune landscapes of EOCRC and LOCRC based on key immune cell subsets, exhaustion markers, soluble cytokines, and metabolic capacity, we seek to improve early detection, enable more timely and personalized treatment, and ultimately identify individuals under 50 at high risk for EOCRC before tumors become clinically detectable.20252025-12-1520252025-01-0120252025-01-01journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/11268/16617reponame:ABACUS. Repositorio de Producción Científicainstname:Universidad Europea (UEM)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:abacus.universidadeuropea.com:11268/166172026-06-11T12:41:27Z
dc.title.none.fl_str_mv Differences in the peripheral blood immune landscape between early-onset and late-onset colorectal cancer
title Differences in the peripheral blood immune landscape between early-onset and late-onset colorectal cancer
spellingShingle Differences in the peripheral blood immune landscape between early-onset and late-onset colorectal cancer
Sánchez-Menéndez, Clara
Neoplasias colorrectales
Diagnóstico precoz
Inmunidad
Cáncer
Medicina preventiva
Investigación médica
Goal 3: Ensure healthy lives and promote well-being for all at all ages
title_short Differences in the peripheral blood immune landscape between early-onset and late-onset colorectal cancer
title_full Differences in the peripheral blood immune landscape between early-onset and late-onset colorectal cancer
title_fullStr Differences in the peripheral blood immune landscape between early-onset and late-onset colorectal cancer
title_full_unstemmed Differences in the peripheral blood immune landscape between early-onset and late-onset colorectal cancer
title_sort Differences in the peripheral blood immune landscape between early-onset and late-onset colorectal cancer
dc.creator.none.fl_str_mv Sánchez-Menéndez, Clara
Rodríguez-Pérez, Jaime
Fuertes, Daniel
Leguizamon, Valentina
González-Sanmartin, María
Mateos, Elena
Cervero, Miguel
San José Martínez, Esther
Sanz, Gonzalo
Álvaro, Edurne
Et. al.
author Sánchez-Menéndez, Clara
author_facet Sánchez-Menéndez, Clara
Rodríguez-Pérez, Jaime
Fuertes, Daniel
Leguizamon, Valentina
González-Sanmartin, María
Mateos, Elena
Cervero, Miguel
San José Martínez, Esther
Sanz, Gonzalo
Álvaro, Edurne
Et. al.
author_role author
author2 Rodríguez-Pérez, Jaime
Fuertes, Daniel
Leguizamon, Valentina
González-Sanmartin, María
Mateos, Elena
Cervero, Miguel
San José Martínez, Esther
Sanz, Gonzalo
Álvaro, Edurne
Et. al.
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv
dc.subject.none.fl_str_mv Neoplasias colorrectales
Diagnóstico precoz
Inmunidad
Cáncer
Medicina preventiva
Investigación médica
Goal 3: Ensure healthy lives and promote well-being for all at all ages
topic Neoplasias colorrectales
Diagnóstico precoz
Inmunidad
Cáncer
Medicina preventiva
Investigación médica
Goal 3: Ensure healthy lives and promote well-being for all at all ages
description This study aims to discover novel immune biomarkers specific to EOCRC that may permit the development of a non-invasive, peripheral blood-based “liquid Immunoscore” that may integrate specific quantitative measurements. By contrasting the immune landscapes of EOCRC and LOCRC based on key immune cell subsets, exhaustion markers, soluble cytokines, and metabolic capacity, we seek to improve early detection, enable more timely and personalized treatment, and ultimately identify individuals under 50 at high risk for EOCRC before tumors become clinically detectable.
publishDate 2025
dc.date.none.fl_str_mv 2025
2025-12-15
2025
2025-01-01
2025
2025-01-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/11268/16617
url https://hdl.handle.net/11268/16617
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:ABACUS. Repositorio de Producción Científica
instname:Universidad Europea (UEM)
instname_str Universidad Europea (UEM)
reponame_str ABACUS. Repositorio de Producción Científica
collection ABACUS. Repositorio de Producción Científica
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869423582613864448
score 15,811543

Similares en LA Referencia