Differences in the peripheral blood immune landscape between early-onset and late-onset colorectal cancer
This study aims to discover novel immune biomarkers specific to EOCRC that may permit the development of a non-invasive, peripheral blood-based “liquid Immunoscore” that may integrate specific quantitative measurements. By contrasting the immune landscapes of EOCRC and LOCRC based on key immune cell...
| Autores: | , , , , , , , , , , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 2025 |
| País: | España |
| Institución: | Universidad Europea (UEM) |
| Repositorio: | ABACUS. Repositorio de Producción Científica |
| Idioma: | inglés |
| OAI Identifier: | oai:abacus.universidadeuropea.com:11268/16617 |
| Acceso en línea: | https://hdl.handle.net/11268/16617 |
| Access Level: | acceso abierto |
| Palabra clave: | Neoplasias colorrectales Diagnóstico precoz Inmunidad Cáncer Medicina preventiva Investigación médica Goal 3: Ensure healthy lives and promote well-being for all at all ages |
| Sumario: | This study aims to discover novel immune biomarkers specific to EOCRC that may permit the development of a non-invasive, peripheral blood-based “liquid Immunoscore” that may integrate specific quantitative measurements. By contrasting the immune landscapes of EOCRC and LOCRC based on key immune cell subsets, exhaustion markers, soluble cytokines, and metabolic capacity, we seek to improve early detection, enable more timely and personalized treatment, and ultimately identify individuals under 50 at high risk for EOCRC before tumors become clinically detectable. |
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