Sustainable extraction techniques for obtaining antioxidant and anti-inflammatory compounds from the Lamiaceae and Asteraceae species

This article belongs to the Special Issue Phenolic Compounds in Herbs: Characterization, Antioxidant Properties and Health Benefits.

Detalles Bibliográficos
Autores: Villalva, Marisol, Santoyo, Susana, Salas-Perez, Lilia, Siles-Sánchez, María de las Nieves, García-Risco, Mónica R., Fornari, Tiziana, Reglero, Guillermo, Jaime, Laura
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/263456
Acceso en línea:http://hdl.handle.net/10261/263456
Access Level:acceso abierto
Palabra clave:Achillea millefolium
Phenolic composition
Origanum majorana
Sustainable extraction
Anti-inflammatory activity
Antioxidant activity
id ES_df2fc14968fae6e32d7b9503aa3d3c03
oai_identifier_str oai:digital.csic.es:10261/263456
network_acronym_str ES
network_name_str España
repository_id_str
spelling Sustainable extraction techniques for obtaining antioxidant and anti-inflammatory compounds from the Lamiaceae and Asteraceae speciesVillalva, MarisolSantoyo, SusanaSalas-Perez, LiliaSiles-Sánchez, María de las NievesGarcía-Risco, Mónica R.Fornari, TizianaReglero, GuillermoJaime, LauraAchillea millefoliumPhenolic compositionOriganum majoranaSustainable extractionAnti-inflammatory activityAntioxidant activityThis article belongs to the Special Issue Phenolic Compounds in Herbs: Characterization, Antioxidant Properties and Health Benefits.Melissa officinalis L. and Origanum majorana L., within Lamiaceae family, and Calendula officinalis L. and Achillea millefolium L., within the Asteraceae, have been considered a good source of bioactive ingredients with health benefits. In this study, the supercritical fluid extraction (SFE) using pure CO2, and the ultrasound assisted extraction (UAE) were proposed as green techniques to obtain plant-based extracts with potential antioxidant and anti-inflammatory activities. Higher values of total phenolic content and antioxidant activity were achieved in UAE ethanol:water (50:50, v/v) extracts. Meanwhile, UAE pure ethanol extracts showed greater anti-inflammatory activity. RP-HPLC-PAD-ESI-QTOF-MS/MS analysis showed a vast number of phenolic compounds in the extracts, including unreported ones. O. majorana ethanol:water extract presented the highest content of phenolics and antioxidant activity; among its composition, both rosmarinic acid and luteolin glucoside derivatives were abundant. The pure ethanol extract of A. millefolium resulted in an important content of caffeoylquinic acid derivatives, luteolin-7-O-glucoside and flavonoid aglycones, which could be related to the remarkable inhibition of TNF-α, IL-1β and IL-6 cytokines. Besides, borneol and camphor, found in the volatile fraction of A. millefolium, could contributed to this latter activity. Thus, this study points out that O. majorana and A. millefolium are considered a promising source of bioactive ingredients with potential use in health promotion.Authors thanks to the Spanish Government (Project: PID2019-110183RB-C22/AEI/10.13039/501100011033) and Comunidad Autónoma de Madrid (ALIBIRD2020-CM (S2018/BAA-4343)) for financial support.Peer reviewedMultidisciplinary Digital Publishing InstituteMinisterio de Ciencia, Innovación y Universidades (España)Agencia Estatal de Investigación (España)Comunidad de MadridConsejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202220222021info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionhttp://hdl.handle.net/10261/263456reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2019-110183RB-C22S2018/BAA-4343/ALIBIRD2020-CMhttps://doi.org/10.3390/foods10092067Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/2634562026-05-22T06:33:51Z
dc.title.none.fl_str_mv Sustainable extraction techniques for obtaining antioxidant and anti-inflammatory compounds from the Lamiaceae and Asteraceae species
title Sustainable extraction techniques for obtaining antioxidant and anti-inflammatory compounds from the Lamiaceae and Asteraceae species
spellingShingle Sustainable extraction techniques for obtaining antioxidant and anti-inflammatory compounds from the Lamiaceae and Asteraceae species
Villalva, Marisol
Achillea millefolium
Phenolic composition
Origanum majorana
Sustainable extraction
Anti-inflammatory activity
Antioxidant activity
title_short Sustainable extraction techniques for obtaining antioxidant and anti-inflammatory compounds from the Lamiaceae and Asteraceae species
title_full Sustainable extraction techniques for obtaining antioxidant and anti-inflammatory compounds from the Lamiaceae and Asteraceae species
title_fullStr Sustainable extraction techniques for obtaining antioxidant and anti-inflammatory compounds from the Lamiaceae and Asteraceae species
title_full_unstemmed Sustainable extraction techniques for obtaining antioxidant and anti-inflammatory compounds from the Lamiaceae and Asteraceae species
title_sort Sustainable extraction techniques for obtaining antioxidant and anti-inflammatory compounds from the Lamiaceae and Asteraceae species
dc.creator.none.fl_str_mv Villalva, Marisol
Santoyo, Susana
Salas-Perez, Lilia
Siles-Sánchez, María de las Nieves
García-Risco, Mónica R.
Fornari, Tiziana
Reglero, Guillermo
Jaime, Laura
author Villalva, Marisol
author_facet Villalva, Marisol
Santoyo, Susana
Salas-Perez, Lilia
Siles-Sánchez, María de las Nieves
García-Risco, Mónica R.
Fornari, Tiziana
Reglero, Guillermo
Jaime, Laura
author_role author
author2 Santoyo, Susana
Salas-Perez, Lilia
Siles-Sánchez, María de las Nieves
García-Risco, Mónica R.
Fornari, Tiziana
Reglero, Guillermo
Jaime, Laura
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Ministerio de Ciencia, Innovación y Universidades (España)
Agencia Estatal de Investigación (España)
Comunidad de Madrid
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Achillea millefolium
Phenolic composition
Origanum majorana
Sustainable extraction
Anti-inflammatory activity
Antioxidant activity
topic Achillea millefolium
Phenolic composition
Origanum majorana
Sustainable extraction
Anti-inflammatory activity
Antioxidant activity
description This article belongs to the Special Issue Phenolic Compounds in Herbs: Characterization, Antioxidant Properties and Health Benefits.
publishDate 2021
dc.date.none.fl_str_mv 2021
2022
2022
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/263456
url http://hdl.handle.net/10261/263456
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
#PLACEHOLDER_PARENT_METADATA_VALUE#
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2019-110183RB-C22
S2018/BAA-4343/ALIBIRD2020-CM
https://doi.org/10.3390/foods10092067
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869422041638109184
score 15,811543

Similares en LA Referencia