Qualitative assessment of AHL secretion by AV-T variants of WT A. baumannii AB5075, deleted ΔcavA mutant and ΔcavA+cavA complemented strain [Dataset]
Cultures of each strain were spot plated on a soft agar mixed with A. tumefaciens traG-lacZ biosensor strain and supplemented with X-Gal and IPTG. The blue halo indicates AHL production by A. baumannii which triggers the cleavage of X-gal by the A. tumefaciens biosensor strain. Empty miniTn7 control...
| Autores: | , , , , |
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| Formato: | conjunto de datos |
| Estado: | Versión publicada |
| Fecha de publicación: | 2024 |
| País: | España |
| Recursos: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositorio: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/372659 |
| Acesso em linha: | http://hdl.handle.net/10261/372659 https://doi.org/10.20350/digitalCSIC/16683 |
| Access Level: | acceso abierto |
| Palavra-chave: | Throughput screening approach Modulating quorum sensing Current treatment options Baumannii &# 8217 Ultimately governing virulence Adaptive antibiotic resistance Opportunistic nosocomial pathogen High potential target Acinetobacter baumannii </ Ac ), cava Baumannii </ Virulence regulation Increasing resistance Cava ac Vivo </ Various aspects Using drna Study uncovers Signalling cascade Second messengers Resort antibiotics Pathogenic success Mortality rates Leading position Inversely regulated Intrabacterial signalling High morbidity Gmp systems First time Exopolysaccharide production Established paradigm Directly proportional Cyclic di Cyclic amp gy Crucial mediator Central regulator Bacterial physiology |
| Resumo: | Cultures of each strain were spot plated on a soft agar mixed with A. tumefaciens traG-lacZ biosensor strain and supplemented with X-Gal and IPTG. The blue halo indicates AHL production by A. baumannii which triggers the cleavage of X-gal by the A. tumefaciens biosensor strain. Empty miniTn7 controls are presented in S8 Fig. |
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