Improving Vaccine-Induced Immunity: Can Baseline Predict Outcome?

Immune signatures measured at baseline and immediately prior to vaccination may predict the immune response to vaccination. Such pre-vaccine assessment might allow not only population-based, but also more personalized vaccination strategies ('precision vaccination'). If baseline immune sig...

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Detalles Bibliográficos
Autores: Tsang, John S., Dobaño, Carlota, 1969-, VanDamme, Pierre, Moncunill Piñas, Gemma, Marchant, Arnaud, Othman, Rym Ben, Sadarangani, Manish, Koff, Wayne C., Kollmann, Tobias R.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/162635
Acceso en línea:https://hdl.handle.net/2445/162635
Access Level:acceso abierto
Palabra clave:Vacunació
Immunitat
Vaccination
Immunity
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spelling Improving Vaccine-Induced Immunity: Can Baseline Predict Outcome?Tsang, John S.Dobaño, Carlota, 1969-VanDamme, PierreMoncunill Piñas, GemmaMarchant, ArnaudOthman, Rym BenSadarangani, ManishKoff, Wayne C.Kollmann, Tobias R.VacunacióImmunitatVaccinationImmunityImmune signatures measured at baseline and immediately prior to vaccination may predict the immune response to vaccination. Such pre-vaccine assessment might allow not only population-based, but also more personalized vaccination strategies ('precision vaccination'). If baseline immune signatures are predictive, the underlying mechanism they reflect may also determine vaccination outcome. Thus, baseline signatures might contribute to identifying interventional targets to be modulated prior to vaccination in order to improve vaccination responses. This concept has the potential to transform vaccination strategies and usher in a new approach to improve global health.Elsevier B.V.2020info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/162635Articles publicats en revistes (ISGlobal)reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció del document publicat a: http://dx.doi.org/10.1016/j.it.2020.04.001Trends In Immunology , 2020 , Online ahead of printhttp://dx.doi.org/ 10.1016/j.it.2020.04.001cc-by-nc-nd (c) Elsevier, 2020http://creativecommons.org/licenses/by-nc-nd/3.0/es/info:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/1626352026-05-27T06:46:51Z
dc.title.none.fl_str_mv Improving Vaccine-Induced Immunity: Can Baseline Predict Outcome?
title Improving Vaccine-Induced Immunity: Can Baseline Predict Outcome?
spellingShingle Improving Vaccine-Induced Immunity: Can Baseline Predict Outcome?
Tsang, John S.
Vacunació
Immunitat
Vaccination
Immunity
title_short Improving Vaccine-Induced Immunity: Can Baseline Predict Outcome?
title_full Improving Vaccine-Induced Immunity: Can Baseline Predict Outcome?
title_fullStr Improving Vaccine-Induced Immunity: Can Baseline Predict Outcome?
title_full_unstemmed Improving Vaccine-Induced Immunity: Can Baseline Predict Outcome?
title_sort Improving Vaccine-Induced Immunity: Can Baseline Predict Outcome?
dc.creator.none.fl_str_mv Tsang, John S.
Dobaño, Carlota, 1969-
VanDamme, Pierre
Moncunill Piñas, Gemma
Marchant, Arnaud
Othman, Rym Ben
Sadarangani, Manish
Koff, Wayne C.
Kollmann, Tobias R.
author Tsang, John S.
author_facet Tsang, John S.
Dobaño, Carlota, 1969-
VanDamme, Pierre
Moncunill Piñas, Gemma
Marchant, Arnaud
Othman, Rym Ben
Sadarangani, Manish
Koff, Wayne C.
Kollmann, Tobias R.
author_role author
author2 Dobaño, Carlota, 1969-
VanDamme, Pierre
Moncunill Piñas, Gemma
Marchant, Arnaud
Othman, Rym Ben
Sadarangani, Manish
Koff, Wayne C.
Kollmann, Tobias R.
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Vacunació
Immunitat
Vaccination
Immunity
topic Vacunació
Immunitat
Vaccination
Immunity
description Immune signatures measured at baseline and immediately prior to vaccination may predict the immune response to vaccination. Such pre-vaccine assessment might allow not only population-based, but also more personalized vaccination strategies ('precision vaccination'). If baseline immune signatures are predictive, the underlying mechanism they reflect may also determine vaccination outcome. Thus, baseline signatures might contribute to identifying interventional targets to be modulated prior to vaccination in order to improve vaccination responses. This concept has the potential to transform vaccination strategies and usher in a new approach to improve global health.
publishDate 2020
dc.date.none.fl_str_mv 2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/162635
url https://hdl.handle.net/2445/162635
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: http://dx.doi.org/10.1016/j.it.2020.04.001
Trends In Immunology , 2020 , Online ahead of print
http://dx.doi.org/ 10.1016/j.it.2020.04.001
dc.rights.none.fl_str_mv cc-by-nc-nd (c) Elsevier, 2020
http://creativecommons.org/licenses/by-nc-nd/3.0/es/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc-by-nc-nd (c) Elsevier, 2020
http://creativecommons.org/licenses/by-nc-nd/3.0/es/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier B.V.
publisher.none.fl_str_mv Elsevier B.V.
dc.source.none.fl_str_mv Articles publicats en revistes (ISGlobal)
reponame:Dipòsit Digital de la UB
instname:Universidad de Barcelona
instname_str Universidad de Barcelona
reponame_str Dipòsit Digital de la UB
collection Dipòsit Digital de la UB
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.301603

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