Seafood Consumption, Omega-3 Fatty Acids Intake, and Life-Time Prevalence of Depression in the PREDIMED-Plus Trial

BACKGROUND: The aim of this analysis was to ascertain the type of relationship between fish and seafood consumption, omega-3 polyunsaturated fatty acids (ω-3 PUFA) intake, and depression prevalence. METHODS: Cross-sectional analyses of the PREDIMED-Plus trial. Fish and seafood consumption and ω-3 PU...

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Detalles Bibliográficos
Autores: Sánchez-Villegas, Almudena, Alvarez Pérez, Jacqueline, Toledo Atucha, Estefanía, Salas Salvadó, Jordi, Ortega Azorín, Carolina, Zomeño Fajardo, María Dolores, Vioque, Jesús, Martínez, J. Alfredo, 1957-, Romaguera, Dora, Pérez López, Jessica, López Miranda, José, Estruch Riba, Ramon, Bueno Cavanillas, Aurora, Arós, Fernando, Tur, Josep Antoni, Tinahones, Francisco J., Lecea, Oscar, Martín Sánchez, Vicente, Ortega Calvo, Manuel, Vázquez, Clotilde, Pintó Sala, Xavier, Vidal i Cortada, Josep, Daimiel, Lidia, Delgado Rodríguez, Miguel, Matía Martín, Pilar, Corella Piquer, Dolores, Díaz López, Andrés, Babio, Nancy, Muñoz Pérez, Miguel Ángel, Fitó Colomer, Montserrat, García de la Hera, Manuela, Abete, Itziar, García Ríos, Antonio, Ros Rahola, Emilio, Ruiz Canela, Miguel, Martínez-González, Miguel Ángel, 1957-, Izquierdo, Marisol, Serra Majem, Lluís
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2018
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/157577
Acceso en línea:https://hdl.handle.net/2445/157577
Access Level:acceso abierto
Palabra clave:Assaigs clínics
Depressió psíquica
Àcids grassos omega-3
Dietoteràpia
Clinical trials
Mental depression
Omega-3 fatty acids
Diet therapy
Descripción
Sumario:BACKGROUND: The aim of this analysis was to ascertain the type of relationship between fish and seafood consumption, omega-3 polyunsaturated fatty acids (ω-3 PUFA) intake, and depression prevalence. METHODS: Cross-sectional analyses of the PREDIMED-Plus trial. Fish and seafood consumption and ω-3 PUFA intake were assessed through a validated food-frequency questionnaire. Self-reported life-time medical diagnosis of depression or use of antidepressants was considered as outcome. Depressive symptoms were collected by the Beck Depression Inventory-II. Logistic regression models were used to estimate the association between seafood products and ω-3 PUFA consumption and depression. Multiple linear regression models were fitted to assess the association between fish and long-chain (LC) ω-3 PUFA intake and depressive symptoms. RESULTS: Out of 6587 participants, there were 1367 cases of depression. Total seafood consumption was not associated with depression. The odds ratios (ORs) (95% confidence intervals (CIs)) for the 2nd, 3rd, and 4th quintiles of consumption of fatty fish were 0.77 (0.63⁻0.94), 0.71 (0.58⁻0.87), and 0.78 (0.64⁻0.96), respectively, and p for trend = 0.759. Moderate intake of total LC ω-3 PUFA (approximately 0.5⁻1 g/day) was significantly associated with a lower prevalence of depression. CONCLUSION: In our study, moderate fish and LC ω-3 PUFA intake, but not high intake, was associated with lower odds of depression suggesting a U-shaped relationship.

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