Seafood Consumption, Omega-3 Fatty Acids Intake, and Life-Time Prevalence of Depression in the PREDIMED-Plus Trial

Background: The aim of this analysis was to ascertain the type of relationship between fish and seafood consumption, omega-3 polyunsaturated fatty acids (-3 PUFA) intake, and depression prevalence. Methods: Cross-sectional analyses of the PREDIMED-Plus trial. Fish and seafood consumption and -3 PUFA...

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Detalles Bibliográficos
Autores: Sanchez-Villegas, Almudena, Alvarez-Perez, Jacqueline, Toledo, Estefania, Salas-Salvado, Jordi, Ortega-Azorin, Carolina, Dolores Zomeno, Maria, Vioque, Jesus, Alfredo Martinez, Jose, Romaguera, Dora, Perez-Lopez, Jessica, Lopez-Miranda, Jose, Estruch, Ramon, Bueno-Cavanillas, Aurora, Aros, Fernando, Tur, Josep A., Tinahones, Francisco J., Lecea, Oscar, Martin, Vicente, Ortega-Calvo, M., Vazquez, Clotilde, Pinto, Xavier, Vidal, Josep, Daimiel, Lidia, Delgado-Rodriguez, Miguel, Matia, Pilar, Corella, Dolores, Diaz-Lopez, Andres, Babio, Nancy, Angel Munoz, Miguel, Fito, Montserrat, Garcia de la Hera, Manoli, Abete, Itziar, Garcia-Rios, Antonio, Ros, Emilio, Ruiz-Canela, Miguel, Angel Martinez-Gonzalez, Miguel, Izquierdo, Marisol, Serra-Majem, Lluis
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2018
País:España
Institución:Instituto de Investigación Biomédica y Sanitaria de Alicante (ISABIAL)
Repositorio:r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
OAI Identifier:oai:isabial.fundanetsuite.com:p2880
Acceso en línea:https://isabial.portalinvestigacion.com/publicaciones2880
Access Level:acceso abierto
Palabra clave:fish
omega-3
eicosapentaenoic acid
docosahexaenoic acid
depression
Descripción
Sumario:Background: The aim of this analysis was to ascertain the type of relationship between fish and seafood consumption, omega-3 polyunsaturated fatty acids (-3 PUFA) intake, and depression prevalence. Methods: Cross-sectional analyses of the PREDIMED-Plus trial. Fish and seafood consumption and -3 PUFA intake were assessed through a validated food-frequency questionnaire. Self-reported life-time medical diagnosis of depression or use of antidepressants was considered as outcome. Depressive symptoms were collected by the Beck Depression Inventory-II. Logistic regression models were used to estimate the association between seafood products and -3 PUFA consumption and depression. Multiple linear regression models were fitted to assess the association between fish and long-chain (LC) -3 PUFA intake and depressive symptoms. Results: Out of 6587 participants, there were 1367 cases of depression. Total seafood consumption was not associated with depression. The odds ratios (ORs) (95% confidence intervals (CIs)) for the 2nd, 3rd, and 4th quintiles of consumption of fatty fish were 0.77 (0.63-0.94), 0.71 (0.58-0.87), and 0.78 (0.64-0.96), respectively, and p for trend = 0.759. Moderate intake of total LC -3 PUFA (approximately 0.5-1 g/day) was significantly associated with a lower prevalence of depression. Conclusion: In our study, moderate fish and LC -3 PUFA intake, but not high intake, was associated with lower odds of depression suggesting a U-shaped relationship.

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