New approaches to the synthesis of pyridinium N-heteroarylaminides
Different substituted pyridinium N-heteroarylaminides have been prepared in one step from N-aminopyridinium iodide and the corresponding heteroaryl halide by two alternative routes. The use of Pd catalysis allowed the easy preparation of products from the less reactive haloheterocycles. The use of w...
| Autores: | , , |
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| Tipo de documento: | artigo |
| Data de publicação: | 2008 |
| País: | España |
| Recursos: | Universidad de Alcalá (UAH) |
| Repositório: | e_Buah Biblioteca Digital Universidad de Alcalá |
| Idioma: | inglês |
| OAI Identifier: | oai:ebuah.uah.es:10017/2691 |
| Acesso em linha: | http://hdl.handle.net/10017/2691 https://dx.doi.org/10.1016/j.tet.2008.06.024 |
| Access Level: | Acceso aberto |
| Palavra-chave: | Palladium-catalyzed amination Regioselective synthesis Radical Cyclization Suzuki reaction Aryl bromides Inner salts Aminides Derivatives N-(2'-azinyl)aminides N-2'-Pyridylaminide Chemistry, Organic Bioquímica Ciencia Biochemistry Science |
| Resumo: | Different substituted pyridinium N-heteroarylaminides have been prepared in one step from N-aminopyridinium iodide and the corresponding heteroaryl halide by two alternative routes. The use of Pd catalysis allowed the easy preparation of products from the less reactive haloheterocycles. The use of water as a solvent in conjunction with microwave heating dramatically diminishes the reaction time without having an adverse effect on reaction yields. |
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