Mediterranean spotted fever in Spain, 1997-2014: Epidemiological situation based on hospitalization records

INTRODUCTION: Mediterranean spotted fever (MSF) is a zoonotic disease caused by Rickettsia conorii. In Spain, deficiencies in the official reporting result in misreporting of this disease. This study aims to describe the clinical and temporal-spatial characteristics of MSF hospitalizations between 1...

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Detalles Bibliográficos
Autores: Herrador, Zaida, Fernandez-Martinez, Amalia, Gomez-Barroso, Diana, Leon-Gomez, Inmaculada, Vieira, Carmen, Muro, Antonio, Benito, Agustin
Tipo de recurso: artículo
Fecha de publicación:2017
País:España
Institución:Instituto de Salud Carlos III (ISCIII)
Repositorio:Repisalud
Idioma:inglés
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/6930
Acceso en línea:http://hdl.handle.net/20.500.12105/6930
Access Level:acceso abierto
Palabra clave:Adolescent
Adult
Aged
Alcoholism
Boutonneuse Fever
Chronic Disease
Comorbidity
Diabetes Mellitus
Female
Hospital Records
Hospitalization
Host-Pathogen Interactions
Humans
International Classification of Diseases
Linear Models
Liver Diseases
Male
Middle Aged
Patient Discharge
Retrospective Studies
Rickettsia conorii
Spain
Syndrome
Young Adult
Descripción
Sumario:INTRODUCTION: Mediterranean spotted fever (MSF) is a zoonotic disease caused by Rickettsia conorii. In Spain, deficiencies in the official reporting result in misreporting of this disease. This study aims to describe the clinical and temporal-spatial characteristics of MSF hospitalizations between 1997 and 2014. MATERIALS AND METHODS: We performed a retrospective descriptive study using the Hospitalization Minimum Data Set (CMBD). All CMBD's hospital discharges with ICD-9 CM code 082.1 were analyzed. Hospitalization rates were calculated and clinical characteristics were described. Spatial distribution of cases and their temporal behavior were also assessed. RESULTS: A total of 4,735 hospitalizations with MSF diagnosis were recorded during the study period, out of which 62.2% were male, mean age of 48. Diabetes mellitus, alcohol dependence syndrome, and chronic liver disease occurred in 10.8%, 2.4% and 2.8% hospitalizations, respectively. The median annual hospitalization rate showed a decreasing trend from a maximum of 12.9 in 1997 to a minimum rate of 3.1 in 2014. Most admissions occurred during the summer, showing a significant annual seasonal behavior. Important regional differences were found. DISCUSSION: Although MSF hospitalization rates have decreased considerably, it remains a public health problem due to its severity and economic impact. Therefore, it would be desirable to improve its oversight and surveillance.