T lymphocyte subsets in Mediterranean spotted fever
[EN]Several studies have previously suggested the possible role of a T lymphocyte suppressor population in infections by species of the genus Rickettsia. In 15 patients with Mediterranean spotted fever (MSF), we quantified, during the acute and convalescent phases of the disease, the peripheral bloo...
| Autores: | , , |
|---|---|
| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 1988 |
| País: | España |
| Institución: | Universidad de Salamanca (USAL) |
| Repositorio: | GREDOS. Repositorio Institucional de la Universidad de Salamanca |
| OAI Identifier: | oai:gredos.usal.es:10366/169170 |
| Acceso en línea: | http://hdl.handle.net/10366/169170 |
| Access Level: | acceso embargado |
| Palabra clave: | Mediterranean spotted fever, Boutonneuse Fever, Rickettsia conorii infection, T lymphyte Mediterranean spotted fever Boutonneuse fever Rickettsia conorii infection T lymphyte T-Lymphocytes Leukocyte Count Boutonneuse Fever Humans 32 Ciencias Médicas humanos recuento de leucocitos linfocitos T fiebre botonosa |
| Sumario: | [EN]Several studies have previously suggested the possible role of a T lymphocyte suppressor population in infections by species of the genus Rickettsia. In 15 patients with Mediterranean spotted fever (MSF), we quantified, during the acute and convalescent phases of the disease, the peripheral blood lymphocyte populations using monoclonal antibodies that recognize CD3+, CD4+, CD8+, CD38+ and CD20+ cells. In three cases a reversal in the normal ratio of T lymphocyte helper-inducer/suppressor-cytotoxic subsets was detected lasting, in two of them, up to the fifth week of the disease. This disturbance was always weak and lacked clinical significance. |
|---|