Deleterious effect of trimethoprim-sulfamethoxazole in Mediterranean spotted fever

[EN]In a series of 10 patients with Mediterranean spotted fever (MSF) (two of whom developed severe forms of the disease), trimethoprim-sulfamethoxazole (TS) was not an effective therapy; moreover, it appeared the drug increased the pathogenic potential of R. cononii. In the opinion of the authors a...

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Detalles Bibliográficos
Autores: Ruiz Beltrán, R., Herrero Herrero, José Ignacio
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:1992
País:España
Institución:Universidad de Salamanca (USAL)
Repositorio:GREDOS. Repositorio Institucional de la Universidad de Salamanca
OAI Identifier:oai:gredos.usal.es:10366/169203
Acceso en línea:http://hdl.handle.net/10366/169203
Access Level:acceso abierto
Palabra clave:Trimethoprim-sulfamethoxazole
Mediterranean spotted fever
Boutonneuse fever
Rickettsia conorii infection
Aged
Trimethoprim
Boutonneuse Fever
Humans
32 Ciencias Médicas
humanos
anciano
fiebre botonosa
trimetoprim
Descripción
Sumario:[EN]In a series of 10 patients with Mediterranean spotted fever (MSF) (two of whom developed severe forms of the disease), trimethoprim-sulfamethoxazole (TS) was not an effective therapy; moreover, it appeared the drug increased the pathogenic potential of R. cononii. In the opinion of the authors and according to these results, TS cannot be considered an effective therapy for MSF.