Additional file 6 of Aβ oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer’s disease

Additional file 6: Fig. S6. RIPK3 inhibition does not alter Aβo-induced microgliosis in wild-type mice. (A, B) Representative micrographs and quantitative analysis of brain sections from wild-type mice treated as indicated in the images, immunostained with anti-Iba1 antibody (scale bar, 200 μm). The...

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Detalles Bibliográficos
Autores: Salvadores, Natalia, Moreno-González, Inés, Gámez, Nazaret, Quiroz, Gabriel, Vegas-Gómez, Laura, Escandón, Marcela, Jiménez-Reyes, Sebastián, Vitorica, Javier, Gutiérrez, Antonia, Soto, Claudio
Tipo de recurso: conjunto de datos
Fecha de publicación:2022
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/331128
Acceso en línea:http://hdl.handle.net/10261/331128
Access Level:acceso abierto
Palabra clave:Alzheimer’s disease
Amyloid-β oligomers
Necroptosis
Microglia
Neurodegeneration
Neuroprotection
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spelling Additional file 6 of Aβ oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer’s diseaseSalvadores, NataliaMoreno-González, InésGámez, NazaretQuiroz, GabrielVegas-Gómez, LauraEscandón, MarcelaJiménez-Reyes, SebastiánVitorica, JavierGutiérrez, AntoniaSoto, ClaudioSoto, ClaudioAlzheimer’s diseaseAmyloid-β oligomersNecroptosisMicrogliaNeurodegenerationNeuroprotectionAdditional file 6: Fig. S6. RIPK3 inhibition does not alter Aβo-induced microgliosis in wild-type mice. (A, B) Representative micrographs and quantitative analysis of brain sections from wild-type mice treated as indicated in the images, immunostained with anti-Iba1 antibody (scale bar, 200 μm). The data are presented as mean ± S.E.M. and were analyzed by one-way ANOVA followed by Bonferroni post-test. *p < 0.05; **p < 0.01.Fondecyt FONDAP ISCIII CIBERNED Junta de Andalucia Consejería de Economía y Conocimiento MICIN Ramon y Cajal Program National Institutes of Health.Peer reviewedFigshareFondo Nacional de Desarrollo Científico y Tecnológico (Chile)Fondo de Financiamiento de Centros de Investigación en Áreas Prioritarias (Chile)Instituto de Salud Carlos IIICentro Investigación Biomédica en Red Enfermedades Neurodegenerativas (España)Junta de AndalucíaMinisterio de Ciencia e Innovación (España)National Institutes of Health (US)Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202320232022info:eu-repo/semantics/datasethttp://purl.org/coar/resource_type/c_ddb1image/tiffhttp://hdl.handle.net/10261/331128reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)InglésSalvadores, Natalia; Moreno-González, Inés; Gámez, Nazaret; Quiroz, Gabriel; Vegas-Gómez, Laura; Escandón, Marcela; Jiménez, Sebastián; Vitorica, Javier; Gutiérrez, Antonia; Soto, Claudio; Court, Felipe A. Aβ oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer's disease. https://doi.org/10.1186/s40478-022-01332-9 . http://hdl.handle.net/10261/295796https://doi.org/10.6084/m9.figshare.19336247.v1Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/3311282026-05-22T06:33:51Z
dc.title.none.fl_str_mv Additional file 6 of Aβ oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer’s disease
title Additional file 6 of Aβ oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer’s disease
spellingShingle Additional file 6 of Aβ oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer’s disease
Salvadores, Natalia
Alzheimer’s disease
Amyloid-β oligomers
Necroptosis
Microglia
Neurodegeneration
Neuroprotection
title_short Additional file 6 of Aβ oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer’s disease
title_full Additional file 6 of Aβ oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer’s disease
title_fullStr Additional file 6 of Aβ oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer’s disease
title_full_unstemmed Additional file 6 of Aβ oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer’s disease
title_sort Additional file 6 of Aβ oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer’s disease
dc.creator.none.fl_str_mv Salvadores, Natalia
Moreno-González, Inés
Gámez, Nazaret
Quiroz, Gabriel
Vegas-Gómez, Laura
Escandón, Marcela
Jiménez-Reyes, Sebastián
Vitorica, Javier
Gutiérrez, Antonia
Soto, Claudio
Soto, Claudio
author Salvadores, Natalia
author_facet Salvadores, Natalia
Moreno-González, Inés
Gámez, Nazaret
Quiroz, Gabriel
Vegas-Gómez, Laura
Escandón, Marcela
Jiménez-Reyes, Sebastián
Vitorica, Javier
Gutiérrez, Antonia
Soto, Claudio
author_role author
author2 Moreno-González, Inés
Gámez, Nazaret
Quiroz, Gabriel
Vegas-Gómez, Laura
Escandón, Marcela
Jiménez-Reyes, Sebastián
Vitorica, Javier
Gutiérrez, Antonia
Soto, Claudio
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Fondo Nacional de Desarrollo Científico y Tecnológico (Chile)
Fondo de Financiamiento de Centros de Investigación en Áreas Prioritarias (Chile)
Instituto de Salud Carlos III
Centro Investigación Biomédica en Red Enfermedades Neurodegenerativas (España)
Junta de Andalucía
Ministerio de Ciencia e Innovación (España)
National Institutes of Health (US)
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Alzheimer’s disease
Amyloid-β oligomers
Necroptosis
Microglia
Neurodegeneration
Neuroprotection
topic Alzheimer’s disease
Amyloid-β oligomers
Necroptosis
Microglia
Neurodegeneration
Neuroprotection
description Additional file 6: Fig. S6. RIPK3 inhibition does not alter Aβo-induced microgliosis in wild-type mice. (A, B) Representative micrographs and quantitative analysis of brain sections from wild-type mice treated as indicated in the images, immunostained with anti-Iba1 antibody (scale bar, 200 μm). The data are presented as mean ± S.E.M. and were analyzed by one-way ANOVA followed by Bonferroni post-test. *p < 0.05; **p < 0.01.
publishDate 2022
dc.date.none.fl_str_mv 2022
2023
2023
dc.type.none.fl_str_mv info:eu-repo/semantics/dataset
http://purl.org/coar/resource_type/c_ddb1
format dataset
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/331128
url http://hdl.handle.net/10261/331128
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Salvadores, Natalia; Moreno-González, Inés; Gámez, Nazaret; Quiroz, Gabriel; Vegas-Gómez, Laura; Escandón, Marcela; Jiménez, Sebastián; Vitorica, Javier; Gutiérrez, Antonia; Soto, Claudio; Court, Felipe A. Aβ oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer's disease. https://doi.org/10.1186/s40478-022-01332-9 . http://hdl.handle.net/10261/295796
https://doi.org/10.6084/m9.figshare.19336247.v1
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv image/tiff
dc.publisher.none.fl_str_mv Figshare
publisher.none.fl_str_mv Figshare
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.81155

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