Additional file 9 of Aβ oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer’s disease

Additional file 9: Fig. S9. TNF-α alone is not sufficient to trigger neuronal necroptosis. (G, H) Representative micrographs and quantitative measurements of neurons treated for 72 h with CMctrl, CMAβ, TNF-α, and with CMctrl/TNF-α, immunolabeled with anti-acetylated tubulin antibody (scale bar, 200...

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Detalhes bibliográficos
Autores: Salvadores, Natalia, Moreno-González, Inés, Gámez, Nazaret, Quiroz, Gabriel, Vegas-Gómez, Laura, Escandón, Marcela, Jiménez-Reyes, Sebastián, Vitorica, Javier, Gutiérrez, Antonia, Soto, Claudio, Court, Felipe A.
Formato: conjunto de datos
Fecha de publicación:2022
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/331131
Acesso em linha:http://hdl.handle.net/10261/331131
Access Level:acceso abierto
Palavra-chave:Alzheimer’s disease
Amyloid-β oligomers
Necroptosis
Microglia
Neurodegeneration
Neuroprotection
Descrição
Resumo:Additional file 9: Fig. S9. TNF-α alone is not sufficient to trigger neuronal necroptosis. (G, H) Representative micrographs and quantitative measurements of neurons treated for 72 h with CMctrl, CMAβ, TNF-α, and with CMctrl/TNF-α, immunolabeled with anti-acetylated tubulin antibody (scale bar, 200 μm). The data are presented as mean ± S.E.M. and were analyzed by one-way ANOVA followed by Bonferroni post-test. *p < 0.05; **p < 0.01.