Arabidopsis thaliana telomeres exhibit euchromatic features

Telomere function is influenced by chromatin structure and organization, which usually involves epigenetic modifications. We describe here the chromatin structure of Arabidopsis thaliana telomeres. Based on the study of six different epigenetic marks we show that Arabidopsis telomeres exhibit euchro...

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Bibliographic Details
Authors: Vaquero Sedas, María Isabel, Gámez Arjona, Francisco M., Vega Palas, Miguel Ángel
Format: article
Status:Published version
Publication Date:2011
Country:España
Institution:Universidad de Sevilla (US)
Repository:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/57488
Online Access:http://hdl.handle.net/11441/57488
https://doi.org/10.1093/nar/gkq1119
Access Level:Open access
Keyword:Arabidopsis
Arabidopsis Proteins
DNA Methylation
DNA-Binding Proteins
Epigenesis
Euchromatin
Histone-Lysine N-Methyltransferase
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oai_identifier_str oai:idus.us.es:11441/57488
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repository_id_str
spelling Arabidopsis thaliana telomeres exhibit euchromatic featuresVaquero Sedas, María IsabelGámez Arjona, Francisco M.Vega Palas, Miguel ÁngelArabidopsisArabidopsis ProteinsDNA MethylationDNA-Binding ProteinsEpigenesisEuchromatinHistone-Lysine N-MethyltransferaseTelomere function is influenced by chromatin structure and organization, which usually involves epigenetic modifications. We describe here the chromatin structure of Arabidopsis thaliana telomeres. Based on the study of six different epigenetic marks we show that Arabidopsis telomeres exhibit euchromatic features. In contrast, subtelomeric regions and telomeric sequences present at interstitial chromosomal loci are heterochromatic. Histone methyltransferases and the chromatin remodeling protein DDM1 control subtelomeric heterochromatin formation. Whereas histone methyltransferases are required for histone H3K9 2Me and non-CpG DNA methylation, DDM1 directs CpG methylation but not H3K9 2Me or non-CpG methylation. These results argue that both kinds of proteins participate in different pathways to reinforce subtelomeric heterochromatin formation.Ministerio de Educación Ciencia BFU2004-01560/BMC, BFU2008-02497/BMC y GEN2003-20859-C03-03/INTEROxford University PressBioquímica Vegetal y Biología MolecularMinisterio de Educación y Ciencia (MEC). España2011info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttp://hdl.handle.net/11441/57488https://doi.org/10.1093/nar/gkq1119reponame:idUS. Depósito de Investigación de la Universidad de Sevillainstname:Universidad de Sevilla (US)InglésNucleic Acids Research, 39 (6), 2007-2017.BFU2004-01560/BMCBFU2008-02497/BMCGEN2003-20859-C03-03/INTER10.1093/nar/gkq1119info:eu-repo/semantics/openAccessoai:idus.us.es:11441/574882026-06-17T12:51:07Z
dc.title.none.fl_str_mv Arabidopsis thaliana telomeres exhibit euchromatic features
title Arabidopsis thaliana telomeres exhibit euchromatic features
spellingShingle Arabidopsis thaliana telomeres exhibit euchromatic features
Vaquero Sedas, María Isabel
Arabidopsis
Arabidopsis Proteins
DNA Methylation
DNA-Binding Proteins
Epigenesis
Euchromatin
Histone-Lysine N-Methyltransferase
title_short Arabidopsis thaliana telomeres exhibit euchromatic features
title_full Arabidopsis thaliana telomeres exhibit euchromatic features
title_fullStr Arabidopsis thaliana telomeres exhibit euchromatic features
title_full_unstemmed Arabidopsis thaliana telomeres exhibit euchromatic features
title_sort Arabidopsis thaliana telomeres exhibit euchromatic features
dc.creator.none.fl_str_mv Vaquero Sedas, María Isabel
Gámez Arjona, Francisco M.
Vega Palas, Miguel Ángel
author Vaquero Sedas, María Isabel
author_facet Vaquero Sedas, María Isabel
Gámez Arjona, Francisco M.
Vega Palas, Miguel Ángel
author_role author
author2 Gámez Arjona, Francisco M.
Vega Palas, Miguel Ángel
author2_role author
author
dc.contributor.none.fl_str_mv Bioquímica Vegetal y Biología Molecular
Ministerio de Educación y Ciencia (MEC). España
dc.subject.none.fl_str_mv Arabidopsis
Arabidopsis Proteins
DNA Methylation
DNA-Binding Proteins
Epigenesis
Euchromatin
Histone-Lysine N-Methyltransferase
topic Arabidopsis
Arabidopsis Proteins
DNA Methylation
DNA-Binding Proteins
Epigenesis
Euchromatin
Histone-Lysine N-Methyltransferase
description Telomere function is influenced by chromatin structure and organization, which usually involves epigenetic modifications. We describe here the chromatin structure of Arabidopsis thaliana telomeres. Based on the study of six different epigenetic marks we show that Arabidopsis telomeres exhibit euchromatic features. In contrast, subtelomeric regions and telomeric sequences present at interstitial chromosomal loci are heterochromatic. Histone methyltransferases and the chromatin remodeling protein DDM1 control subtelomeric heterochromatin formation. Whereas histone methyltransferases are required for histone H3K9 2Me and non-CpG DNA methylation, DDM1 directs CpG methylation but not H3K9 2Me or non-CpG methylation. These results argue that both kinds of proteins participate in different pathways to reinforce subtelomeric heterochromatin formation.
publishDate 2011
dc.date.none.fl_str_mv 2011
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11441/57488
https://doi.org/10.1093/nar/gkq1119
url http://hdl.handle.net/11441/57488
https://doi.org/10.1093/nar/gkq1119
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Nucleic Acids Research, 39 (6), 2007-2017.
BFU2004-01560/BMC
BFU2008-02497/BMC
GEN2003-20859-C03-03/INTER
10.1093/nar/gkq1119
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Oxford University Press
publisher.none.fl_str_mv Oxford University Press
dc.source.none.fl_str_mv reponame:idUS. Depósito de Investigación de la Universidad de Sevilla
instname:Universidad de Sevilla (US)
instname_str Universidad de Sevilla (US)
reponame_str idUS. Depósito de Investigación de la Universidad de Sevilla
collection idUS. Depósito de Investigación de la Universidad de Sevilla
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869417909094187008
score 15.301603

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