Secondhand exposure to aerosol from electronic cigarettes: pilot study of assessment of tobacco-specific nitrosamine (NNAL) in urine

OBJECTIVE: To assess the levels of a tobacco-specific nitrosamine (NNAL) in non-smokers passively exposed to the second-hand aerosol (SHA) emitted from users of electronic cigarettes (e-cigarettes). METHOD: We conducted an observational study involving 55 non-smoking volunteers divided into three gr...

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Autores: Martínez-Sánchez, Jose M., Ballbé, Montse, Pérez Ortuño, Raúl, 1976-, Fu, Marcela, Sureda, Xisca, Pascual Esteban, José A., Peruga, Armando, Fernández, Esteve
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2018
País:España
Institución:Universitat Pompeu Fabra
Repositorio:Repositorio Digital de la UPF
OAI Identifier:oai:repositori.upf.edu:10230/42155
Acceso en línea:http://hdl.handle.net/10230/42155
http://dx.doi.org/10.1016/j.gaceta.2018.07.016
Access Level:acceso embargado
Palabra clave:Biomarcadores
Biomarkers
Cigarrillo electrónico
Electronic cigarette
Nitrosaminas
Nitrosamines
Second-hand aerosol
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spelling Secondhand exposure to aerosol from electronic cigarettes: pilot study of assessment of tobacco-specific nitrosamine (NNAL) in urineMartínez-Sánchez, Jose M.Ballbé, MontsePérez Ortuño, Raúl, 1976-Fu, MarcelaSureda, XiscaPascual Esteban, José A.Peruga, ArmandoFernández, EsteveBiomarcadoresBiomarkersCigarrillo electrónicoElectronic cigaretteNitrosaminasNitrosaminesSecond-hand aerosolOBJECTIVE: To assess the levels of a tobacco-specific nitrosamine (NNAL) in non-smokers passively exposed to the second-hand aerosol (SHA) emitted from users of electronic cigarettes (e-cigarettes). METHOD: We conducted an observational study involving 55 non-smoking volunteers divided into three groups: 25 living at home with conventional smokers, 6 living with e-cigarette users, and 24 in control homes (smoke-free homes). We obtained urine samples from all volunteers to determine NNAL. RESULTS: We detected NNAL in the urine of volunteers exposed to e-cigarettes (median:0.55 pg/mL; interquartile range: 0.26-2.94 pg/mL). The percentage of urine samples with quantifiable NNAL differed significantly among the three groups of homes: 29.2%, 66.7% and 76.0%, respectively (p=0.004). CONCLUSIONS: We found NNAL nitrosamine in urine samples from people exposed to SHA from e-cigarettes. However, these results could be confirmed with more studies with larger sample sizes.Elsevier201920192018info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttp://hdl.handle.net/10230/42155http://dx.doi.org/10.1016/j.gaceta.2018.07.016reponame:Repositorio Digital de la UPFinstname:Universitat Pompeu FabraInglésGaceta Sanitaria. 2019;33(6):575-80213-9111/© 2018 SESPAS. Publicado por Elsevier España, S.L.U. Este es un artículo Open Access bajo la licencia CC BY-NC-ND (http://creativecommons.org/licenses/by-nc-nd/4.0/).http://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/embargoedAccessoai:repositori.upf.edu:10230/421552026-06-12T07:21:37Z
dc.title.none.fl_str_mv Secondhand exposure to aerosol from electronic cigarettes: pilot study of assessment of tobacco-specific nitrosamine (NNAL) in urine
title Secondhand exposure to aerosol from electronic cigarettes: pilot study of assessment of tobacco-specific nitrosamine (NNAL) in urine
spellingShingle Secondhand exposure to aerosol from electronic cigarettes: pilot study of assessment of tobacco-specific nitrosamine (NNAL) in urine
Martínez-Sánchez, Jose M.
Biomarcadores
Biomarkers
Cigarrillo electrónico
Electronic cigarette
Nitrosaminas
Nitrosamines
Second-hand aerosol
title_short Secondhand exposure to aerosol from electronic cigarettes: pilot study of assessment of tobacco-specific nitrosamine (NNAL) in urine
title_full Secondhand exposure to aerosol from electronic cigarettes: pilot study of assessment of tobacco-specific nitrosamine (NNAL) in urine
title_fullStr Secondhand exposure to aerosol from electronic cigarettes: pilot study of assessment of tobacco-specific nitrosamine (NNAL) in urine
title_full_unstemmed Secondhand exposure to aerosol from electronic cigarettes: pilot study of assessment of tobacco-specific nitrosamine (NNAL) in urine
title_sort Secondhand exposure to aerosol from electronic cigarettes: pilot study of assessment of tobacco-specific nitrosamine (NNAL) in urine
dc.creator.none.fl_str_mv Martínez-Sánchez, Jose M.
Ballbé, Montse
Pérez Ortuño, Raúl, 1976-
Fu, Marcela
Sureda, Xisca
Pascual Esteban, José A.
Peruga, Armando
Fernández, Esteve
author Martínez-Sánchez, Jose M.
author_facet Martínez-Sánchez, Jose M.
Ballbé, Montse
Pérez Ortuño, Raúl, 1976-
Fu, Marcela
Sureda, Xisca
Pascual Esteban, José A.
Peruga, Armando
Fernández, Esteve
author_role author
author2 Ballbé, Montse
Pérez Ortuño, Raúl, 1976-
Fu, Marcela
Sureda, Xisca
Pascual Esteban, José A.
Peruga, Armando
Fernández, Esteve
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Biomarcadores
Biomarkers
Cigarrillo electrónico
Electronic cigarette
Nitrosaminas
Nitrosamines
Second-hand aerosol
topic Biomarcadores
Biomarkers
Cigarrillo electrónico
Electronic cigarette
Nitrosaminas
Nitrosamines
Second-hand aerosol
description OBJECTIVE: To assess the levels of a tobacco-specific nitrosamine (NNAL) in non-smokers passively exposed to the second-hand aerosol (SHA) emitted from users of electronic cigarettes (e-cigarettes). METHOD: We conducted an observational study involving 55 non-smoking volunteers divided into three groups: 25 living at home with conventional smokers, 6 living with e-cigarette users, and 24 in control homes (smoke-free homes). We obtained urine samples from all volunteers to determine NNAL. RESULTS: We detected NNAL in the urine of volunteers exposed to e-cigarettes (median:0.55 pg/mL; interquartile range: 0.26-2.94 pg/mL). The percentage of urine samples with quantifiable NNAL differed significantly among the three groups of homes: 29.2%, 66.7% and 76.0%, respectively (p=0.004). CONCLUSIONS: We found NNAL nitrosamine in urine samples from people exposed to SHA from e-cigarettes. However, these results could be confirmed with more studies with larger sample sizes.
publishDate 2018
dc.date.none.fl_str_mv 2018
2019
2019
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10230/42155
http://dx.doi.org/10.1016/j.gaceta.2018.07.016
url http://hdl.handle.net/10230/42155
http://dx.doi.org/10.1016/j.gaceta.2018.07.016
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Gaceta Sanitaria. 2019;33(6):575-8
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/embargoedAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv embargoedAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositorio Digital de la UPF
instname:Universitat Pompeu Fabra
instname_str Universitat Pompeu Fabra
reponame_str Repositorio Digital de la UPF
collection Repositorio Digital de la UPF
repository.name.fl_str_mv
repository.mail.fl_str_mv
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