Secondhand exposure to aerosol from electronic cigarettes: pilot study of assessment of tobacco-specific nitrosamine (NNAL) in urine

OBJECTIVE: To assess the levels of a tobacco-specific nitrosamine (NNAL) in non-smokers passively exposed to the second-hand aerosol (SHA) emitted from users of electronic cigarettes (e-cigarettes). METHOD: We conducted an observational study involving 55 non-smoking volunteers divided into three gr...

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Detalles Bibliográficos
Autores: Martínez-Sánchez, Jose M., Ballbé, Montse, Pérez Ortuño, Raúl, 1976-, Fu, Marcela, Sureda, Xisca, Pascual Esteban, José A., Peruga, Armando, Fernández, Esteve
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2018
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10230/42155
Acceso en línea:http://hdl.handle.net/10230/42155
http://dx.doi.org/10.1016/j.gaceta.2018.07.016
Access Level:acceso embargado
Palabra clave:Biomarcadores
Biomarkers
Cigarrillo electrónico
Electronic cigarette
Nitrosaminas
Nitrosamines
Second-hand aerosol
Descripción
Sumario:OBJECTIVE: To assess the levels of a tobacco-specific nitrosamine (NNAL) in non-smokers passively exposed to the second-hand aerosol (SHA) emitted from users of electronic cigarettes (e-cigarettes). METHOD: We conducted an observational study involving 55 non-smoking volunteers divided into three groups: 25 living at home with conventional smokers, 6 living with e-cigarette users, and 24 in control homes (smoke-free homes). We obtained urine samples from all volunteers to determine NNAL. RESULTS: We detected NNAL in the urine of volunteers exposed to e-cigarettes (median:0.55 pg/mL; interquartile range: 0.26-2.94 pg/mL). The percentage of urine samples with quantifiable NNAL differed significantly among the three groups of homes: 29.2%, 66.7% and 76.0%, respectively (p=0.004). CONCLUSIONS: We found NNAL nitrosamine in urine samples from people exposed to SHA from e-cigarettes. However, these results could be confirmed with more studies with larger sample sizes.