Secondhand exposure to aerosol from electronic cigarettes: pilot study of assessment of tobacco-specific nitrosamine (NNAL) in urine

Objective: to assess the levels of a tobacco-specific nitrosamine (NNAL) in non-smokers passively exposed to the second-hand aerosol (SHA) emitted from users of electronic cigarettes (e-cigarettes). Method: we conducted an observational study involving 55 non-smoking volunteers divided into three gr...

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Detalhes bibliográficos
Autores: Martínez Sánchez, Jose M., Ballbè i Gibernau, Montse, Pérez Ortuño, Raúl, Fu Balboa, Marcela, Sureda, Xisca, Pascual, José Antonio, Peruga, Armando, Fernández Muñoz, Esteve
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2019
País:España
Recursos:Universidad de Barcelona
Repositório:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/174098
Acesso em linha:https://hdl.handle.net/2445/174098
Access Level:Acceso aberto
Palavra-chave:Cigarretes electròniques
Marcadors bioquímics
Nitrosamines
Electronic cigarettes
Biochemical markers
Nitrosoamines
Descrição
Resumo:Objective: to assess the levels of a tobacco-specific nitrosamine (NNAL) in non-smokers passively exposed to the second-hand aerosol (SHA) emitted from users of electronic cigarettes (e-cigarettes). Method: we conducted an observational study involving 55 non-smoking volunteers divided into three groups: 25 living at home with conventional smokers, 6 living with e-cigarette users, and 24 in control homes (smoke-free homes). We obtained urine samples from all volunteers to determine NNAL. Results: we detected NNAL in the urine of volunteers exposed to e-cigarettes (median:0.55 pg/mL; interquartile range: 0.26-2.94 pg/mL). The percentage of urine samples with quantifiable NNAL differed significantly among the three groups of homes: 29.2%, 66.7% and 76.0%, respectively (p=0.004). Conclusions: we found NNAL nitrosamine in urine samples from people exposed to SHA from e-cigarettes. However, these results could be confirmed with more studies with larger sample sizes.