PPARß/d: A Key Therapeutic Target in Metabolic Disorders.

Research in recent years on peroxisome proliferator-activated receptor (PPAR)ß/d indicates that it plays a key role in the maintenance of energy homeostasis, both at the cellular level and within the organism as a whole. PPARß/d activation might help prevent the development of metabolic disorders, i...

ver descrição completa

Detalhes bibliográficos
Autores: Palomer X, Barroso E, Pizarro-Delgado J, Peña L, Botteri G, Zarei M, Aguilar D, Montori-Grau M, Vázquez-Carrera M
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2018
País:España
Recursos:Fundació Sant Joan de Déu
Repositório:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
OAI Identifier:oai:fsjd.fundanetsuite.com:p13989
Acesso em linha:https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=13989
Access Level:Acceso aberto
Palavra-chave:PPARß/d
dyslipidaemia
non-alcoholic fatty liver disease
obesity
type 2 diabetes mellitus
id ES_aab574a29a90455c1ccf3d8da0aa7218
oai_identifier_str oai:fsjd.fundanetsuite.com:p13989
network_acronym_str ES
network_name_str España
repository_id_str
spelling PPARß/d: A Key Therapeutic Target in Metabolic Disorders.Palomer XBarroso EPizarro-Delgado JPeña LBotteri GZarei MAguilar DMontori-Grau MVázquez-Carrera MPPARß/ddyslipidaemianon-alcoholic fatty liver diseaseobesitytype 2 diabetes mellitusResearch in recent years on peroxisome proliferator-activated receptor (PPAR)ß/d indicates that it plays a key role in the maintenance of energy homeostasis, both at the cellular level and within the organism as a whole. PPARß/d activation might help prevent the development of metabolic disorders, including obesity, dyslipidaemia, type 2 diabetes mellitus and non-alcoholic fatty liver disease. This review highlights research findings on the PPARß/d regulation of energy metabolism and the development of diseases related to altered cellular and body metabolism. It also describes the potential of the pharmacological activation of PPARß/d as a treatment for human metabolic disorders.MDPI2018info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=13989INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESISSN: 16616596ISSNe: 14220067reponame:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déuinstname:Fundació Sant Joan de DéuInglésinfo:eu-repo/semantics/openAccessoai:fsjd.fundanetsuite.com:p139892026-05-27T12:37:41Z
dc.title.none.fl_str_mv PPARß/d: A Key Therapeutic Target in Metabolic Disorders.
title PPARß/d: A Key Therapeutic Target in Metabolic Disorders.
spellingShingle PPARß/d: A Key Therapeutic Target in Metabolic Disorders.
Palomer X
PPARß/d
dyslipidaemia
non-alcoholic fatty liver disease
obesity
type 2 diabetes mellitus
title_short PPARß/d: A Key Therapeutic Target in Metabolic Disorders.
title_full PPARß/d: A Key Therapeutic Target in Metabolic Disorders.
title_fullStr PPARß/d: A Key Therapeutic Target in Metabolic Disorders.
title_full_unstemmed PPARß/d: A Key Therapeutic Target in Metabolic Disorders.
title_sort PPARß/d: A Key Therapeutic Target in Metabolic Disorders.
dc.creator.none.fl_str_mv Palomer X
Barroso E
Pizarro-Delgado J
Peña L
Botteri G
Zarei M
Aguilar D
Montori-Grau M
Vázquez-Carrera M
author Palomer X
author_facet Palomer X
Barroso E
Pizarro-Delgado J
Peña L
Botteri G
Zarei M
Aguilar D
Montori-Grau M
Vázquez-Carrera M
author_role author
author2 Barroso E
Pizarro-Delgado J
Peña L
Botteri G
Zarei M
Aguilar D
Montori-Grau M
Vázquez-Carrera M
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv PPARß/d
dyslipidaemia
non-alcoholic fatty liver disease
obesity
type 2 diabetes mellitus
topic PPARß/d
dyslipidaemia
non-alcoholic fatty liver disease
obesity
type 2 diabetes mellitus
description Research in recent years on peroxisome proliferator-activated receptor (PPAR)ß/d indicates that it plays a key role in the maintenance of energy homeostasis, both at the cellular level and within the organism as a whole. PPARß/d activation might help prevent the development of metabolic disorders, including obesity, dyslipidaemia, type 2 diabetes mellitus and non-alcoholic fatty liver disease. This review highlights research findings on the PPARß/d regulation of energy metabolism and the development of diseases related to altered cellular and body metabolism. It also describes the potential of the pharmacological activation of PPARß/d as a treatment for human metabolic disorders.
publishDate 2018
dc.date.none.fl_str_mv 2018
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=13989
url https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=13989
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
ISSN: 16616596
ISSNe: 14220067
reponame:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname:Fundació Sant Joan de Déu
instname_str Fundació Sant Joan de Déu
reponame_str r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
collection r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869416205166575616
score 15,198674

Registros relacionados