PPARß/d: A Key Therapeutic Target in Metabolic Disorders.
Research in recent years on peroxisome proliferator-activated receptor (PPAR)ß/d indicates that it plays a key role in the maintenance of energy homeostasis, both at the cellular level and within the organism as a whole. PPARß/d activation might help prevent the development of metabolic disorders, i...
| Autores: | , , , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2018 |
| País: | España |
| Institución: | Fundació Sant Joan de Déu |
| Repositorio: | r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu |
| OAI Identifier: | oai:fsjd.fundanetsuite.com:p13989 |
| Acceso en línea: | https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=13989 |
| Access Level: | acceso abierto |
| Palabra clave: | PPARß/d dyslipidaemia non-alcoholic fatty liver disease obesity type 2 diabetes mellitus |
| Sumario: | Research in recent years on peroxisome proliferator-activated receptor (PPAR)ß/d indicates that it plays a key role in the maintenance of energy homeostasis, both at the cellular level and within the organism as a whole. PPARß/d activation might help prevent the development of metabolic disorders, including obesity, dyslipidaemia, type 2 diabetes mellitus and non-alcoholic fatty liver disease. This review highlights research findings on the PPARß/d regulation of energy metabolism and the development of diseases related to altered cellular and body metabolism. It also describes the potential of the pharmacological activation of PPARß/d as a treatment for human metabolic disorders. |
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