CMV and Immunosenescence: from basics to clinics

Alone among herpesviruses, persistent Cytomegalovirus (CMV) markedly alters the numbers and proportions of peripheral immune cells in infected-vs-uninfected people. Because the rate of CMV infection increases with age in most countries, it has been suggested that it drives or at least exacerbates “i...

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Autores: Solana, Rafael, Tarazona, Raquel, Aiello, Allison E., Akbar, Arne N., Appay, Victor, Beswick, Mark, Bosch, Jos A., Campos, Carmen, Cantisán, Sara, Cicin Sain, Luca, Derhovanessian, Evelyna, Ferrando Martínez, Sara, Frasca, Daniela, Fulöp, Tamas, Govind, Sheila, Grubeck Loebenstein, Beatrix, Hill, Ann, Hurme, Mikko, Kern, Florian, Larbi, Anis, López-Botet, M. (Miguel), Maier, Andrea B., McElhaney, Janet E., Moss, Paul, Naumova, Elissaveta, Nikolich Zugich, Janko, Pera, Alejandra, Rector, Jerrarld L., Riddell, Natalie, Sanchez Correa, Beatriz, Sansoni, Paolo, Sauce, Delphine, Lier, Rene van, Wang, George C., Wills, Mark R., Zielinski, Maciej, Pawelec, Graham
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2012
País:España
Institución:Universitat Pompeu Fabra
Repositorio:Repositorio Digital de la UPF
OAI Identifier:oai:repositori.upf.edu:10230/23187
Acceso en línea:http://hdl.handle.net/10230/23187
http://dx.doi.org/10.1186/1742-4933-9-23
Access Level:acceso abierto
Palabra clave:Immunitat cel·lular
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repository_id_str
spelling CMV and Immunosenescence: from basics to clinicsSolana, RafaelTarazona, RaquelAiello, Allison E.Akbar, Arne N.Appay, VictorBeswick, MarkBosch, Jos A.Campos, CarmenCantisán, SaraCicin Sain, LucaDerhovanessian, EvelynaFerrando Martínez, SaraFrasca, DanielaFulöp, TamasGovind, SheilaGrubeck Loebenstein, BeatrixHill, AnnHurme, MikkoKern, FlorianLarbi, AnisLópez-Botet, M. (Miguel)Maier, Andrea B.McElhaney, Janet E.Moss, PaulNaumova, ElissavetaNikolich Zugich, JankoPera, AlejandraRector, Jerrarld L.Riddell, NatalieSanchez Correa, BeatrizSansoni, PaoloSauce, DelphineLier, Rene vanWang, George C.Wills, Mark R.Zielinski, MaciejPawelec, GrahamImmunitat cel·lularAlone among herpesviruses, persistent Cytomegalovirus (CMV) markedly alters the numbers and proportions of peripheral immune cells in infected-vs-uninfected people. Because the rate of CMV infection increases with age in most countries, it has been suggested that it drives or at least exacerbates “immunosenescence”. This contention remains controversial and was the primary subject of the Third International Workshop on CMV & Immunosenescence which was held in Cordoba, Spain, 15-16th March, 2012. Discussions focused on several main themes including the effects of CMV on adaptive immunity and immunosenescence, characterization of CMV-specific T cells, impact of CMV infection and ageing on innate immunity, and finally, most important, the clinical implications of immunosenescence and CMV infection. Here we summarize the major findings of this workshop.The Workshop was partially supported by the University of Cordoba and the Spanish Ministry of Science (SAF2011-16169-E)BioMed Central201520152012info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttp://hdl.handle.net/10230/23187http://dx.doi.org/10.1186/1742-4933-9-23reponame:Repositorio Digital de la UPFinstname:Universitat Pompeu FabraInglésImmunity & Ageing. 2012; 9: 23info:eu-repo/grantAgreement/ES/3PN/SAF2011-16169© 2012 Solana et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.http://creativecommons.org/licenses/by/2.0info:eu-repo/semantics/openAccessoai:repositori.upf.edu:10230/231872026-06-12T07:21:37Z
dc.title.none.fl_str_mv CMV and Immunosenescence: from basics to clinics
title CMV and Immunosenescence: from basics to clinics
spellingShingle CMV and Immunosenescence: from basics to clinics
Solana, Rafael
Immunitat cel·lular
title_short CMV and Immunosenescence: from basics to clinics
title_full CMV and Immunosenescence: from basics to clinics
title_fullStr CMV and Immunosenescence: from basics to clinics
title_full_unstemmed CMV and Immunosenescence: from basics to clinics
title_sort CMV and Immunosenescence: from basics to clinics
dc.creator.none.fl_str_mv Solana, Rafael
Tarazona, Raquel
Aiello, Allison E.
Akbar, Arne N.
Appay, Victor
Beswick, Mark
Bosch, Jos A.
Campos, Carmen
Cantisán, Sara
Cicin Sain, Luca
Derhovanessian, Evelyna
Ferrando Martínez, Sara
Frasca, Daniela
Fulöp, Tamas
Govind, Sheila
Grubeck Loebenstein, Beatrix
Hill, Ann
Hurme, Mikko
Kern, Florian
Larbi, Anis
López-Botet, M. (Miguel)
Maier, Andrea B.
McElhaney, Janet E.
Moss, Paul
Naumova, Elissaveta
Nikolich Zugich, Janko
Pera, Alejandra
Rector, Jerrarld L.
Riddell, Natalie
Sanchez Correa, Beatriz
Sansoni, Paolo
Sauce, Delphine
Lier, Rene van
Wang, George C.
Wills, Mark R.
Zielinski, Maciej
Pawelec, Graham
author Solana, Rafael
author_facet Solana, Rafael
Tarazona, Raquel
Aiello, Allison E.
Akbar, Arne N.
Appay, Victor
Beswick, Mark
Bosch, Jos A.
Campos, Carmen
Cantisán, Sara
Cicin Sain, Luca
Derhovanessian, Evelyna
Ferrando Martínez, Sara
Frasca, Daniela
Fulöp, Tamas
Govind, Sheila
Grubeck Loebenstein, Beatrix
Hill, Ann
Hurme, Mikko
Kern, Florian
Larbi, Anis
López-Botet, M. (Miguel)
Maier, Andrea B.
McElhaney, Janet E.
Moss, Paul
Naumova, Elissaveta
Nikolich Zugich, Janko
Pera, Alejandra
Rector, Jerrarld L.
Riddell, Natalie
Sanchez Correa, Beatriz
Sansoni, Paolo
Sauce, Delphine
Lier, Rene van
Wang, George C.
Wills, Mark R.
Zielinski, Maciej
Pawelec, Graham
author_role author
author2 Tarazona, Raquel
Aiello, Allison E.
Akbar, Arne N.
Appay, Victor
Beswick, Mark
Bosch, Jos A.
Campos, Carmen
Cantisán, Sara
Cicin Sain, Luca
Derhovanessian, Evelyna
Ferrando Martínez, Sara
Frasca, Daniela
Fulöp, Tamas
Govind, Sheila
Grubeck Loebenstein, Beatrix
Hill, Ann
Hurme, Mikko
Kern, Florian
Larbi, Anis
López-Botet, M. (Miguel)
Maier, Andrea B.
McElhaney, Janet E.
Moss, Paul
Naumova, Elissaveta
Nikolich Zugich, Janko
Pera, Alejandra
Rector, Jerrarld L.
Riddell, Natalie
Sanchez Correa, Beatriz
Sansoni, Paolo
Sauce, Delphine
Lier, Rene van
Wang, George C.
Wills, Mark R.
Zielinski, Maciej
Pawelec, Graham
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Immunitat cel·lular
topic Immunitat cel·lular
description Alone among herpesviruses, persistent Cytomegalovirus (CMV) markedly alters the numbers and proportions of peripheral immune cells in infected-vs-uninfected people. Because the rate of CMV infection increases with age in most countries, it has been suggested that it drives or at least exacerbates “immunosenescence”. This contention remains controversial and was the primary subject of the Third International Workshop on CMV & Immunosenescence which was held in Cordoba, Spain, 15-16th March, 2012. Discussions focused on several main themes including the effects of CMV on adaptive immunity and immunosenescence, characterization of CMV-specific T cells, impact of CMV infection and ageing on innate immunity, and finally, most important, the clinical implications of immunosenescence and CMV infection. Here we summarize the major findings of this workshop.
publishDate 2012
dc.date.none.fl_str_mv 2012
2015
2015
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10230/23187
http://dx.doi.org/10.1186/1742-4933-9-23
url http://hdl.handle.net/10230/23187
http://dx.doi.org/10.1186/1742-4933-9-23
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Immunity & Ageing. 2012; 9: 23
info:eu-repo/grantAgreement/ES/3PN/SAF2011-16169
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by/2.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/2.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv reponame:Repositorio Digital de la UPF
instname:Universitat Pompeu Fabra
instname_str Universitat Pompeu Fabra
reponame_str Repositorio Digital de la UPF
collection Repositorio Digital de la UPF
repository.name.fl_str_mv
repository.mail.fl_str_mv
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