Genetic regulation of the Achaete-scute complex of Drosophila melanogaster

Mutants in two loci,hairy (h +) andextramacrochaetae (emc +), produce phenotypes corresponding to an excess of function of theachaete-scute complex (AS-C), that is, they cause the appearance of extra chaetae. These mutants, although recessive in normal flies, become dominant in the presence of extra...

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Detalhes bibliográficos
Autores: Moscoso del Prado, J., García-Bellido, Antonio
Formato: artículo
Fecha de publicación:1984
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/47709
Acesso em linha:http://hdl.handle.net/10261/47709
Access Level:acceso embargado
Palavra-chave:Chaetae
Sensillae
Differentiation
Genetic regulation
Drosophila melanogaster
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spelling Genetic regulation of the Achaete-scute complex of Drosophila melanogasterMoscoso del Prado, J.García-Bellido, AntonioChaetaeSensillaeDifferentiationGenetic regulationDrosophila melanogasterMutants in two loci,hairy (h +) andextramacrochaetae (emc +), produce phenotypes corresponding to an excess of function of theachaete-scute complex (AS-C), that is, they cause the appearance of extra chaetae. These mutants, although recessive in normal flies, become dominant in the presence of extra doses of AS-C. Here we study the interactions between these three genes, in an attempt to elucidate their relationships. The results show that the insufficiency produced byh oremc mutants can be titrated by altering the number of copies of AS-C. Moreover, excess of function of AS-C produced by derepression mutants within the complex (Hairy-wing) can also be titrated by altering the number of wild type copies of+ oremc +. These specific interactions indicate that bothh + andemc + code for ldquorepressorsrdquo of AS-C that interact with theachaete andscute region of the complex respectively.Peer reviewedSpringer NatureConsejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]201220121984info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501http://hdl.handle.net/10261/47709reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Ingléshttp://dx.doi.org/10.1007/BF01260345Síinfo:eu-repo/semantics/embargoedAccessoai:digital.csic.es:10261/477092026-05-22T06:33:51Z
dc.title.none.fl_str_mv Genetic regulation of the Achaete-scute complex of Drosophila melanogaster
title Genetic regulation of the Achaete-scute complex of Drosophila melanogaster
spellingShingle Genetic regulation of the Achaete-scute complex of Drosophila melanogaster
Moscoso del Prado, J.
Chaetae
Sensillae
Differentiation
Genetic regulation
Drosophila melanogaster
title_short Genetic regulation of the Achaete-scute complex of Drosophila melanogaster
title_full Genetic regulation of the Achaete-scute complex of Drosophila melanogaster
title_fullStr Genetic regulation of the Achaete-scute complex of Drosophila melanogaster
title_full_unstemmed Genetic regulation of the Achaete-scute complex of Drosophila melanogaster
title_sort Genetic regulation of the Achaete-scute complex of Drosophila melanogaster
dc.creator.none.fl_str_mv Moscoso del Prado, J.
García-Bellido, Antonio
author Moscoso del Prado, J.
author_facet Moscoso del Prado, J.
García-Bellido, Antonio
author_role author
author2 García-Bellido, Antonio
author2_role author
dc.contributor.none.fl_str_mv Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Chaetae
Sensillae
Differentiation
Genetic regulation
Drosophila melanogaster
topic Chaetae
Sensillae
Differentiation
Genetic regulation
Drosophila melanogaster
description Mutants in two loci,hairy (h +) andextramacrochaetae (emc +), produce phenotypes corresponding to an excess of function of theachaete-scute complex (AS-C), that is, they cause the appearance of extra chaetae. These mutants, although recessive in normal flies, become dominant in the presence of extra doses of AS-C. Here we study the interactions between these three genes, in an attempt to elucidate their relationships. The results show that the insufficiency produced byh oremc mutants can be titrated by altering the number of copies of AS-C. Moreover, excess of function of AS-C produced by derepression mutants within the complex (Hairy-wing) can also be titrated by altering the number of wild type copies of+ oremc +. These specific interactions indicate that bothh + andemc + code for ldquorepressorsrdquo of AS-C that interact with theachaete andscute region of the complex respectively.
publishDate 1984
dc.date.none.fl_str_mv 1984
2012
2012
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/47709
url http://hdl.handle.net/10261/47709
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv http://dx.doi.org/10.1007/BF01260345
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/embargoedAccess
eu_rights_str_mv embargoedAccess
dc.publisher.none.fl_str_mv Springer Nature
publisher.none.fl_str_mv Springer Nature
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,198674

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