Developmental Analysis of the Achaete-Scute System of DROSOPHILA MELANOGASTER

The interpretation of the wild-type function of a gene depends on our knowledge of the phenotype caused by its absence. We have first defined the genetic extent of the achaete-scute system by studying the phenotype of different terminal and intercalary deficiencies including these genes. When these...

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Detalles Bibliográficos
Autores: García-Bellido, Antonio, Santamaría, Pedro
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:1978
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/47605
Acceso en línea:http://hdl.handle.net/10261/47605
Access Level:acceso abierto
Palabra clave:Drosophila
Melanogaster
Achaete
Scute
Descripción
Sumario:The interpretation of the wild-type function of a gene depends on our knowledge of the phenotype caused by its absence. We have first defined the genetic extent of the achaete-scute system by studying the phenotype of different terminal and intercalary deficiencies including these genes. When these deficiencies were lethal, we have defined the phenoeffective phase of lethality and studied their phenotype in genetic mosaics (gynandromorphs and mitotic recombination clones). The achaete-scute system affects two functions, one necessary for the differentiation of the embryonic (central?) nervous system and the other necessary for the differentiation of peripheral nervous elements of the chaetes and sensillae of the adult cuticle. The possibility that these functions correspond to differential expression of a single mechanism is discussed.