Cell interactions in the generation of chaetae pattern in Drosophila

We have already shown that theachaetae-scute complex (AS-C) ofDrosophila is regulated by two genes,hairy andextramacrochaetae. Using mutants in these genes, we have analysed how different levels of expression of AS-C affect the pattern of chaetae. The results indicate that the spatial distribution o...

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Detalles Bibliográficos
Autores: Moscoso del Prado, J., García-Bellido, Antonio
Tipo de recurso: artículo
Fecha de publicación:1984
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/47710
Acceso en línea:http://hdl.handle.net/10261/47710
Access Level:acceso embargado
Palabra clave:Chaetae
Differentiation
Genetic regulation
Pattern formation
Drosophila melanogaster
Descripción
Sumario:We have already shown that theachaetae-scute complex (AS-C) ofDrosophila is regulated by two genes,hairy andextramacrochaetae. Using mutants in these genes, we have analysed how different levels of expression of AS-C affect the pattern of chaetae. The results indicate that the spatial distribution of chaetae results from cell interactions, probably by a mechanism of lateral inhibition. The results are discussed in view of the different theories of pattern formation.