Functional characterization of a novel non-coding mutation “Ghent +49A > G” in the iron-responsive element of L-ferritin causing hereditary hyperferritinaemia-cataract syndrome

This study was supported by the Ghent University Special Research Fund (BOF15/GOA/011) to E.D.B. and grant SAF2015-70412-R from Spanish Secretary of Research, Development and Innovation (MINECO), grant 2014 SGR225 (GRE, Grup Rercerca Emergent) from Generalitat de Catalunya and economical support fro...

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Detalles Bibliográficos
Autores: Van de Sompele, Stijn, PECHEUX, Lucie, Couso, Jorge, Meunier, Audrey, Sanchez-Fernandez, Mayka, De Baere, Elfride
Tipo de recurso: artículo
Fecha de publicación:2017
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:20.500.12328/3074
Acceso en línea:http://hdl.handle.net/20.500.12328/3074
http://www.dx.doi.org/10.1038/s41598-017-18326-6
Access Level:acceso abierto
Palabra clave:Síndrome d'hiperferritinèmia-cataracta hereditària
Mutacions
Mutacions heterozigotes
Síndrome de hiperferritinemia-cataracta hereditaria
Mutaciones
Mutaciones heterocigotas
Hereditary hyperferritinemia-cataract syndrome
Mutations
Heterozygous mutations
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Descripción
Sumario:This study was supported by the Ghent University Special Research Fund (BOF15/GOA/011) to E.D.B. and grant SAF2015-70412-R from Spanish Secretary of Research, Development and Innovation (MINECO), grant 2014 SGR225 (GRE, Grup Rercerca Emergent) from Generalitat de Catalunya and economical support from Fundació Internacional Josep Carreras and from Obra Social “la Caixa” Spain to M.S. S.V.d.S. is PhD fellow of the BOF (01D04716). E.D.B. is Senior Clinical Investigator of the FWO (1802215N). Te authors gratefully acknowledge the family who participated in this study.