Endotoxic activity of rough organisms of Brucella species

A rough-specific antigen extracted from the rough species Brucella ovis and lipopolysaccharide extracted from smooth Brucella abortus demonstrated equivalent levels of activity in tests for mouse lethality and limulus lysate clotting activity. Acetone-extracted whole cells of B. ovis and of B. canis...

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Detalles Bibliográficos
Autores: Jones, L.M. (Lois M.)|||/items/3d018183-2235-45be-9645-8a4ff9d0f3c9, Diaz, R. (Ramón)|||/items/5326d716-1718-4b1a-adf2-64bb72a0861c, Berman, D.T. (D. T.)|||/items/219c190a-932f-4f5f-87ba-815c09f7eea2
Tipo de recurso: artículo
Fecha de publicación:1976
País:España
Institución:Universidad de Navarra
Repositorio:Dadun. Depósito Académico Digital de la Universidad de Navarra
Idioma:inglés
OAI Identifier:oai:dadun.unav.edu:10171/29501
Acceso en línea:https://hdl.handle.net/10171/29501
Access Level:acceso abierto
Palabra clave:Brucella immunology
Endotoxins isolation and purification
Lipopolysaccharides toxicity
Polysaccharides
Bacterial toxicity
Descripción
Sumario:A rough-specific antigen extracted from the rough species Brucella ovis and lipopolysaccharide extracted from smooth Brucella abortus demonstrated equivalent levels of activity in tests for mouse lethality and limulus lysate clotting activity. Acetone-extracted whole cells of B. ovis and of B. canis and of a rough mutant of B; abortus had the same toxicity for mice, but it was not possible to extract endotoxin from B. canis by the methods used.