Endotoxic activity of rough organisms of Brucella species

A rough-specific antigen extracted from the rough species Brucella ovis and lipopolysaccharide extracted from smooth Brucella abortus demonstrated equivalent levels of activity in tests for mouse lethality and limulus lysate clotting activity. Acetone-extracted whole cells of B. ovis and of B. canis...

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Bibliographic Details
Authors: Jones, L.M. (Lois M.)|||/items/3d018183-2235-45be-9645-8a4ff9d0f3c9, Diaz, R. (Ramón)|||/items/5326d716-1718-4b1a-adf2-64bb72a0861c, Berman, D.T. (D. T.)|||/items/219c190a-932f-4f5f-87ba-815c09f7eea2
Format: article
Publication Date:1976
Country:España
Institution:Universidad de Navarra
Repository:Dadun. Depósito Académico Digital de la Universidad de Navarra
Language:English
OAI Identifier:oai:dadun.unav.edu:10171/29501
Online Access:https://hdl.handle.net/10171/29501
Access Level:Open access
Keyword:Brucella immunology
Endotoxins isolation and purification
Lipopolysaccharides toxicity
Polysaccharides
Bacterial toxicity
Description
Summary:A rough-specific antigen extracted from the rough species Brucella ovis and lipopolysaccharide extracted from smooth Brucella abortus demonstrated equivalent levels of activity in tests for mouse lethality and limulus lysate clotting activity. Acetone-extracted whole cells of B. ovis and of B. canis and of a rough mutant of B; abortus had the same toxicity for mice, but it was not possible to extract endotoxin from B. canis by the methods used.