From nanometric to giant polyion complex micelles via a hierarchical assembly of dendrimers
PIC (polyion complex) micelles prepared from oppositely charged block copolymers have typical diameters of about 30-50 nm. Attempts to control their size have proven elusive. Since the presence of a neutral hydrophilic block in the copolymers, such as poly(ethylene glycol) (PEG), allows confining th...
| Autores: | , , , |
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| Tipo de documento: | artigo |
| Estado: | Versión aceptada para publicación |
| Data de publicação: | 2025 |
| País: | España |
| Recursos: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositório: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/382099 |
| Acesso em linha: | http://hdl.handle.net/10261/382099 https://api.elsevier.com/content/abstract/scopus_id/85217824321 |
| Access Level: | Acesso embargado |
| Palavra-chave: | Polyion complex Dendrimer Giant micelle Hierarchical assembly PIC http://metadata.un.org/sdg/3 Ensure healthy lives and promote well-being for all at all ages |
| Resumo: | PIC (polyion complex) micelles prepared from oppositely charged block copolymers have typical diameters of about 30-50 nm. Attempts to control their size have proven elusive. Since the presence of a neutral hydrophilic block in the copolymers, such as poly(ethylene glycol) (PEG), allows confining the charged blocks within a core, reducing PEGylation was expected to produce larger micelles to accommodate fewer/smaller PEG chains at the corona. |
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