Health benefits of methylxanthines in cacao and chocolate

One may wonder why methylxanthines are so abundant in beverages used by humans for centuries, or in cola-drinks that have been heavily consumed since their appearance. It is likely that humans have stuck to any brew containing compounds with psychoactive properties, resulting in a better daily life,...

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Authors: Franco, R. (Rafael)|||/items/11f971cd-f36c-4f89-b4d5-8269d33e93fc, Oñatibia, A. (Ainhoa)|||/items/93234b55-365f-4798-a061-1cb3b8b3de03, Martinez-Pinilla, E. (Eva)|||/items/d5984b57-f20c-44bd-907b-365fdfe7b09f
Format: article
Publication Date:2013
Country:España
Institution:Universidad de Navarra
Repository:Dadun. Depósito Académico Digital de la Universidad de Navarra
Language:English
OAI Identifier:oai:dadun.unav.edu:10171/38635
Online Access:https://hdl.handle.net/10171/38635
Access Level:Open access
Keyword:Adenosine
Adenosine receptors
Adenosine receptor antagonist
Caffeine
Theobromine
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spelling Health benefits of methylxanthines in cacao and chocolateFranco, R. (Rafael)|||/items/11f971cd-f36c-4f89-b4d5-8269d33e93fcOñatibia, A. (Ainhoa)|||/items/93234b55-365f-4798-a061-1cb3b8b3de03Martinez-Pinilla, E. (Eva)|||/items/d5984b57-f20c-44bd-907b-365fdfe7b09fAdenosineAdenosine receptorsAdenosine receptor antagonistCaffeineTheobromineOne may wonder why methylxanthines are so abundant in beverages used by humans for centuries, or in cola-drinks that have been heavily consumed since their appearance. It is likely that humans have stuck to any brew containing compounds with psychoactive properties, resulting in a better daily life, i.e., more efficient thinking, exploring, hunting, etc., however, without the serious side effects of drugs of abuse. The physiological effects of methylxanthines have been known for a long time and they are mainly mediated by the so-called adenosine receptors. Caffeine and theobromine are the most abundant methylxanthines in cacao and their physiological effects are notable. Their health-promoting benefits are so remarkable that chocolate is explored as a functional food. The consequences of adenosine receptor blockade by natural compounds present in cacao/chocolate are here reviewed. Palatability and health benefits of methylxanthines, in general, and theobromine, in particular, have further contributed to sustain one of the most innocuous and pleasant habits: chocolate consumption.MDPIDadun. Depósito Académico Digital Universidad de Navarra20152015-06-1720132013-01-0120132013-01-01journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10171/38635reponame:Dadun. Depósito Académico Digital de la Universidad de Navarrainstname:Universidad de NavarraInglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:dadun.unav.edu:10171/386352026-06-21T12:47:57Z
dc.title.none.fl_str_mv Health benefits of methylxanthines in cacao and chocolate
title Health benefits of methylxanthines in cacao and chocolate
spellingShingle Health benefits of methylxanthines in cacao and chocolate
Franco, R. (Rafael)|||/items/11f971cd-f36c-4f89-b4d5-8269d33e93fc
Adenosine
Adenosine receptors
Adenosine receptor antagonist
Caffeine
Theobromine
title_short Health benefits of methylxanthines in cacao and chocolate
title_full Health benefits of methylxanthines in cacao and chocolate
title_fullStr Health benefits of methylxanthines in cacao and chocolate
title_full_unstemmed Health benefits of methylxanthines in cacao and chocolate
title_sort Health benefits of methylxanthines in cacao and chocolate
dc.creator.none.fl_str_mv Franco, R. (Rafael)|||/items/11f971cd-f36c-4f89-b4d5-8269d33e93fc
Oñatibia, A. (Ainhoa)|||/items/93234b55-365f-4798-a061-1cb3b8b3de03
Martinez-Pinilla, E. (Eva)|||/items/d5984b57-f20c-44bd-907b-365fdfe7b09f
author Franco, R. (Rafael)|||/items/11f971cd-f36c-4f89-b4d5-8269d33e93fc
author_facet Franco, R. (Rafael)|||/items/11f971cd-f36c-4f89-b4d5-8269d33e93fc
Oñatibia, A. (Ainhoa)|||/items/93234b55-365f-4798-a061-1cb3b8b3de03
Martinez-Pinilla, E. (Eva)|||/items/d5984b57-f20c-44bd-907b-365fdfe7b09f
author_role author
author2 Oñatibia, A. (Ainhoa)|||/items/93234b55-365f-4798-a061-1cb3b8b3de03
Martinez-Pinilla, E. (Eva)|||/items/d5984b57-f20c-44bd-907b-365fdfe7b09f
author2_role author
author
dc.contributor.none.fl_str_mv Dadun. Depósito Académico Digital Universidad de Navarra
dc.subject.none.fl_str_mv Adenosine
Adenosine receptors
Adenosine receptor antagonist
Caffeine
Theobromine
topic Adenosine
Adenosine receptors
Adenosine receptor antagonist
Caffeine
Theobromine
description One may wonder why methylxanthines are so abundant in beverages used by humans for centuries, or in cola-drinks that have been heavily consumed since their appearance. It is likely that humans have stuck to any brew containing compounds with psychoactive properties, resulting in a better daily life, i.e., more efficient thinking, exploring, hunting, etc., however, without the serious side effects of drugs of abuse. The physiological effects of methylxanthines have been known for a long time and they are mainly mediated by the so-called adenosine receptors. Caffeine and theobromine are the most abundant methylxanthines in cacao and their physiological effects are notable. Their health-promoting benefits are so remarkable that chocolate is explored as a functional food. The consequences of adenosine receptor blockade by natural compounds present in cacao/chocolate are here reviewed. Palatability and health benefits of methylxanthines, in general, and theobromine, in particular, have further contributed to sustain one of the most innocuous and pleasant habits: chocolate consumption.
publishDate 2013
dc.date.none.fl_str_mv 2013
2013-01-01
2013
2013-01-01
2015
2015-06-17
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/10171/38635
url https://hdl.handle.net/10171/38635
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Dadun. Depósito Académico Digital de la Universidad de Navarra
instname:Universidad de Navarra
instname_str Universidad de Navarra
reponame_str Dadun. Depósito Académico Digital de la Universidad de Navarra
collection Dadun. Depósito Académico Digital de la Universidad de Navarra
repository.name.fl_str_mv
repository.mail.fl_str_mv
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