Health benefits of methylxanthines in cacao and chocolate

One may wonder why methylxanthines are so abundant in beverages used by humans for centuries, or in cola-drinks that have been heavily consumed since their appearance. It is likely that humans have stuck to any brew containing compounds with psychoactive properties, resulting in a better daily life,...

Descripción completa

Detalles Bibliográficos
Autores: Franco, R. (Rafael)|||/items/11f971cd-f36c-4f89-b4d5-8269d33e93fc, Oñatibia, A. (Ainhoa)|||/items/93234b55-365f-4798-a061-1cb3b8b3de03, Martinez-Pinilla, E. (Eva)|||/items/d5984b57-f20c-44bd-907b-365fdfe7b09f
Tipo de recurso: artículo
Fecha de publicación:2013
País:España
Institución:Universidad de Navarra
Repositorio:Dadun. Depósito Académico Digital de la Universidad de Navarra
Idioma:inglés
OAI Identifier:oai:dadun.unav.edu:10171/38635
Acceso en línea:https://hdl.handle.net/10171/38635
Access Level:acceso abierto
Palabra clave:Adenosine
Adenosine receptors
Adenosine receptor antagonist
Caffeine
Theobromine
Descripción
Sumario:One may wonder why methylxanthines are so abundant in beverages used by humans for centuries, or in cola-drinks that have been heavily consumed since their appearance. It is likely that humans have stuck to any brew containing compounds with psychoactive properties, resulting in a better daily life, i.e., more efficient thinking, exploring, hunting, etc., however, without the serious side effects of drugs of abuse. The physiological effects of methylxanthines have been known for a long time and they are mainly mediated by the so-called adenosine receptors. Caffeine and theobromine are the most abundant methylxanthines in cacao and their physiological effects are notable. Their health-promoting benefits are so remarkable that chocolate is explored as a functional food. The consequences of adenosine receptor blockade by natural compounds present in cacao/chocolate are here reviewed. Palatability and health benefits of methylxanthines, in general, and theobromine, in particular, have further contributed to sustain one of the most innocuous and pleasant habits: chocolate consumption.