Planar Chiral 1,3-Disubstituted Ferrocenyl Phosphine Gold(I) Catalysts

Planar chiral monodentate 1,3-disubstituted ferrocene phosphines inspired on JohnPhos-type ligands have been synthesized and applied to the enantioselective gold(I) catalyzed [4 + 2] cycloaddition of 1,6-arylenynes. Computational studies rationalized the working mode of the catalyst on the folding o...

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Bibliographic Details
Authors: Caniparoli, Ulysse, Escofet, Imma, Echavarren, Antonio M.
Format: article
Status:Versión aceptada para publicación
Publication Date:2022
Country:España
Institution:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repository:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2072/521681
Online Access:http://hdl.handle.net/2072/521681
https://doi.org/10.1021/acscatal.1c05827
Access Level:Open access
Keyword:54
Description
Summary:Planar chiral monodentate 1,3-disubstituted ferrocene phosphines inspired on JohnPhos-type ligands have been synthesized and applied to the enantioselective gold(I) catalyzed [4 + 2] cycloaddition of 1,6-arylenynes. Computational studies rationalized the working mode of the catalyst on the folding of the substrate in the chiral environment of the ligand involving attractive noncovalent interactions.