Study of brain complexity using information theory tools

The human brain is a complex network that shares and processes information by using the structural paths between areas in order to perform a function. The connectome models the brain as a graph where nodes correspond to brain regions and edges to structural or functional connections. In this thesis,...

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Detalles Bibliográficos
Autor: Bonmatí Coll, Ester
Tipo de recurso: tesis doctoral
Estado:Versión publicada
Fecha de publicación:2016
País:España
Institución:CBUC, CESCA
Repositorio:TDR. Tesis Doctorales en Red
OAI Identifier:oai:www.tdx.cat:10803/404384
Acceso en línea:http://hdl.handle.net/10803/404384
Access Level:acceso abierto
Palabra clave:Connectome
Connectoma
Conectoma
Brain complexity
Complexitat del cervell
Complejidad del cerebro
Information theory
Teoria de la informació
Teoría de la información
Brain networks
Xarxes cerebrals
Redes cerebrales
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Descripción
Sumario:The human brain is a complex network that shares and processes information by using the structural paths between areas in order to perform a function. The connectome models the brain as a graph where nodes correspond to brain regions and edges to structural or functional connections. In this thesis, we investigate and provide new methods to study the brain complexity and improve the understanding of the brain functioning by using information theory. Firstly, we focus on brain parcellation, which is a key step to perform brain studies since determines the regions to be analyzed. Secondly, we focus on the definition of measures to characterize the complexity of the brain networks. Finally, the consistency of the results across healthy subjects using functional or structural connectivity data, demonstrates the flexibility and robustness of the proposed methods