The prostaglandin D2 receptor (PTGDR) gene in asthma and allergic diseases
[EN] The prostaglandin D2 receptor (PTGDR) gene has been associated to asthma and related phenotypes by linking and association studies. Functional studies involving animal models and other expression studies based on in vitro cell models also point to a possible role of polymorphisms in the promote...
| Autores: | , , , , , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2014 |
| País: | España |
| Institución: | Universidad de Salamanca (USAL) |
| Repositorio: | GREDOS. Repositorio Institucional de la Universidad de Salamanca |
| OAI Identifier: | oai:gredos.usal.es:10366/158882 |
| Acceso en línea: | http://hdl.handle.net/10366/158882 |
| Access Level: | acceso abierto |
| Palabra clave: | Asthma Atopy Prostaglandin D(2) Prostaglandin D(2) receptor Genetics Allergy and Immunology 3207.01 Alergias 2409 Genética alergia e inmunología genética |
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The prostaglandin D2 receptor (PTGDR) gene in asthma and allergic diseasesGarcía Solaesa, VirginiaSanz Lozano, Catalina SofíaPadrón-Morales, J.Hernández Hernández, LauraGarcía Sánchez, María AsunciónRivera-Reigada, M.L.Dávila González, Ignacio JesúsLorente-Toledano, F.Isidoro García, MaríaAsthmaAtopyProstaglandin D(2)Prostaglandin D(2) receptorGeneticsAllergy and Immunology3207.01 Alergias2409 Genéticaalergia e inmunologíagenética[EN] The prostaglandin D2 receptor (PTGDR) gene has been associated to asthma and related phenotypes by linking and association studies. Functional studies involving animal models and other expression studies based on in vitro cell models also point to a possible role of polymorphisms in the promoter region, in the differential binding of transcription factors, and thus in PTGDR expression, which appear to be associated to the development of asthma or of susceptibility to the disease.Spanish ‘‘Fondo de Investigación Sanitaria’’ (FIS); Sociedad Española de Alergología e Inmunología Clínica; Fondo Caja de Burgos de ayudas a la Investigación ClínicaElservier202420242014info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://hdl.handle.net/10366/158882reponame:GREDOS. Repositorio Institucional de la Universidad de Salamancainstname:Universidad de Salamanca (USAL)InglésAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:gredos.usal.es:10366/1588822026-06-07T06:28:51Z |
| dc.title.none.fl_str_mv |
The prostaglandin D2 receptor (PTGDR) gene in asthma and allergic diseases |
| title |
The prostaglandin D2 receptor (PTGDR) gene in asthma and allergic diseases |
| spellingShingle |
The prostaglandin D2 receptor (PTGDR) gene in asthma and allergic diseases García Solaesa, Virginia Asthma Atopy Prostaglandin D(2) Prostaglandin D(2) receptor Genetics Allergy and Immunology 3207.01 Alergias 2409 Genética alergia e inmunología genética |
| title_short |
The prostaglandin D2 receptor (PTGDR) gene in asthma and allergic diseases |
| title_full |
The prostaglandin D2 receptor (PTGDR) gene in asthma and allergic diseases |
| title_fullStr |
The prostaglandin D2 receptor (PTGDR) gene in asthma and allergic diseases |
| title_full_unstemmed |
The prostaglandin D2 receptor (PTGDR) gene in asthma and allergic diseases |
| title_sort |
The prostaglandin D2 receptor (PTGDR) gene in asthma and allergic diseases |
| dc.creator.none.fl_str_mv |
García Solaesa, Virginia Sanz Lozano, Catalina Sofía Padrón-Morales, J. Hernández Hernández, Laura García Sánchez, María Asunción Rivera-Reigada, M.L. Dávila González, Ignacio Jesús Lorente-Toledano, F. Isidoro García, María |
| author |
García Solaesa, Virginia |
| author_facet |
García Solaesa, Virginia Sanz Lozano, Catalina Sofía Padrón-Morales, J. Hernández Hernández, Laura García Sánchez, María Asunción Rivera-Reigada, M.L. Dávila González, Ignacio Jesús Lorente-Toledano, F. Isidoro García, María |
| author_role |
author |
| author2 |
Sanz Lozano, Catalina Sofía Padrón-Morales, J. Hernández Hernández, Laura García Sánchez, María Asunción Rivera-Reigada, M.L. Dávila González, Ignacio Jesús Lorente-Toledano, F. Isidoro García, María |
| author2_role |
author author author author author author author author |
| dc.subject.none.fl_str_mv |
Asthma Atopy Prostaglandin D(2) Prostaglandin D(2) receptor Genetics Allergy and Immunology 3207.01 Alergias 2409 Genética alergia e inmunología genética |
| topic |
Asthma Atopy Prostaglandin D(2) Prostaglandin D(2) receptor Genetics Allergy and Immunology 3207.01 Alergias 2409 Genética alergia e inmunología genética |
| description |
[EN] The prostaglandin D2 receptor (PTGDR) gene has been associated to asthma and related phenotypes by linking and association studies. Functional studies involving animal models and other expression studies based on in vitro cell models also point to a possible role of polymorphisms in the promoter region, in the differential binding of transcription factors, and thus in PTGDR expression, which appear to be associated to the development of asthma or of susceptibility to the disease. |
| publishDate |
2014 |
| dc.date.none.fl_str_mv |
2014 2024 2024 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.none.fl_str_mv |
http://hdl.handle.net/10366/158882 |
| url |
http://hdl.handle.net/10366/158882 |
| dc.language.none.fl_str_mv |
Inglés |
| language_invalid_str_mv |
Inglés |
| dc.rights.none.fl_str_mv |
Attribution-NonCommercial-NoDerivatives 4.0 Internacional http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess |
| rights_invalid_str_mv |
Attribution-NonCommercial-NoDerivatives 4.0 Internacional http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| eu_rights_str_mv |
openAccess |
| dc.publisher.none.fl_str_mv |
Elservier |
| publisher.none.fl_str_mv |
Elservier |
| dc.source.none.fl_str_mv |
reponame:GREDOS. Repositorio Institucional de la Universidad de Salamanca instname:Universidad de Salamanca (USAL) |
| instname_str |
Universidad de Salamanca (USAL) |
| reponame_str |
GREDOS. Repositorio Institucional de la Universidad de Salamanca |
| collection |
GREDOS. Repositorio Institucional de la Universidad de Salamanca |
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| repository.mail.fl_str_mv |
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1869411750578749440 |
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15,81155 |